{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Guo Q"],"funding":["National Natural Science Foundation of China","Program of High-level Innovation Talents in Guizhou Province","Program for Natural Science Research in Guizhou Education Department","Guiyang Science and Technology Personnel Training Project"],"pagination":["175"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11857020"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(2)"],"pubmed_abstract":["Vitellogenin (Vg) and the vitellogenin receptor (VgR) play essential roles in insect reproductive development. However, the functions of <i>Vg</i> and <i>VgR</i> genes in <i>Lasioderma serricorne</i>, an important insect pest of stored products, are unknown. We identified and characterized these two genes, designated <i>LsVg</i> and <i>LsVgR</i>, in <i>L. serricorne</i>. The open reading frames of <i>LsVg</i> and <i>LsVgR</i> were 5232 and 5529 bp, encoding 1743 and 1842 amino acid residues, respectively. Both <i>LsVg</i> and <i>LsVgR</i> were predominantly expressed in female adults and exhibited the highest expression in ovaries. The RNAi-mediated silencing of <i>LsVg</i> or <i>LsVgR</i> significantly decreased the average length of ovarian tubes and oocytes and severely affected ovarian"],"journal":["Insects"],"pubmed_title":["Roles of Vitellogenin and Its Receptor Genes in Female Reproduction of the Cigarette Beetle, <i>Lasioderma serricorne</i>."],"pmcid":["PMC11857020"],"funding_grant_id":["GCC[2023]008","[2023]48-19","QJJ-[2023]-024","32160637"],"pubmed_authors":["Yang W","Xu K","Zu M","Liu D","Yan Y","Guo Q"],"additional_accession":[]},"is_claimable":false,"name":"Roles of Vitellogenin and Its Receptor Genes in Female Reproduction of the Cigarette Beetle, <i>Lasioderma serricorne</i>.","description":"Vitellogenin (Vg) and the vitellogenin receptor (VgR) play essential roles in insect reproductive development. However, the functions of <i>Vg</i> and <i>VgR</i> genes in <i>Lasioderma serricorne</i>, an important insect pest of stored products, are unknown. We identified and characterized these two genes, designated <i>LsVg</i> and <i>LsVgR</i>, in <i>L. serricorne</i>. The open reading frames of <i>LsVg</i> and <i>LsVgR</i> were 5232 and 5529 bp, encoding 1743 and 1842 amino acid residues, respectively. Both <i>LsVg</i> and <i>LsVgR</i> were predominantly expressed in female adults and exhibited the highest expression in ovaries. The RNAi-mediated silencing of <i>LsVg</i> or <i>LsVgR</i> significantly decreased the average length of ovarian tubes and oocytes and severely affected ovarian","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2026-04-08T19:50:38.506Z","creation":"2025-04-04T00:12:11.731Z"},"accession":"S-EPMC11857020","cross_references":{"pubmed":["40003805"],"doi":["10.3390/insects16020175"]}}