{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Katugampala Appuhamilage D"],"funding":["The New Zealand Institute for Plant and Food Research Limited's Strategic Science Investment Fund"],"pagination":["129"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11857230"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(2)"],"pubmed_abstract":["<b>Background/Objectives</b>: This study reports the development of a straightforward, efficient, and cost-effective dispersive liquid-liquid microextraction (DLLME) method for the gas chromatography-mass spectrometry (GC-MS) analysis of volatile compounds present in wine. <b>Methods</b>: Four critical parameters were optimised using a D-optimal design to maximise extraction outcomes of the targeted analytes from a 10 mL sample, while minimising interference from other compounds. The analytical characteristics of the method were assessed using 36 target compounds. <b>Results</b>: The method provided satisfactory linearity (correlation coefficients > 0.990), good repeatability for both for intra- and inter-day measurements (RSD < 10.3%), and suitable recoveries of target analytes from both model (83-110%) and real matrices (80-120%). The validated method was subsequently applied to analyse the aroma profile of 30 New Zealand Pinot noir (PN) wine samples. <b>Conclusions</b>: This study contributes to the advancement of analytical techniques available to both industry and researchers to explore the complex aroma profiles of wines."],"journal":["Metabolites"],"pubmed_title":["Development of a Dispersive Liquid-Liquid Microextraction Method for Quantification of Volatile Compounds in Wines Using Gas Chromatography-Mass Spectrometry."],"pmcid":["PMC11857230"],"funding_grant_id":["SSIF, P/471778/20"],"pubmed_authors":["Fedrizzi B","Jelley RE","Pilkington LI","Sherman E","Katugampala Appuhamilage D","Pinu FR"],"additional_accession":[]},"is_claimable":false,"name":"Development of a Dispersive Liquid-Liquid Microextraction Method for Quantification of Volatile Compounds in Wines Using Gas Chromatography-Mass Spectrometry.","description":"<b>Background/Objectives</b>: This study reports the development of a straightforward, efficient, and cost-effective dispersive liquid-liquid microextraction (DLLME) method for the gas chromatography-mass spectrometry (GC-MS) analysis of volatile compounds present in wine. <b>Methods</b>: Four critical parameters were optimised using a D-optimal design to maximise extraction outcomes of the targeted analytes from a 10 mL sample, while minimising interference from other compounds. The analytical characteristics of the method were assessed using 36 target compounds. <b>Results</b>: The method provided satisfactory linearity (correlation coefficients > 0.990), good repeatability for both for intra- and inter-day measurements (RSD < 10.3%), and suitable recoveries of target analytes from both model (83-110%) and real matrices (80-120%). The validated method was subsequently applied to analyse the aroma profile of 30 New Zealand Pinot noir (PN) wine samples. <b>Conclusions</b>: This study contributes to the advancement of analytical techniques available to both industry and researchers to explore the complex aroma profiles of wines.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2025-04-18T21:20:34.019Z","creation":"2025-04-07T09:18:49.347Z"},"accession":"S-EPMC11857230","cross_references":{"pubmed":["39997754"],"doi":["10.3390/metabo15020129"]}}