{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Barbeta E"],"funding":["Instituto de Salud Carlos III"],"pagination":["27"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11861844"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(1)"],"pubmed_abstract":["<h4>Background</h4>The relative contribution of the different components of mechanical power to mortality is a subject of debate and has not been studied in COVID-19. The aim of this study is to evaluate both the total and the relative impact of each of the components of mechanical power on mortality in a well-characterized cohort of patients with COVID-19-induced acute respiratory failure undergoing invasive mechanical ventilation. This is a secondary analysis of the CIBERESUCICOVID project, a multicenter observational cohort study including fifty Spanish intensive care units that included COVID-19 mechanically ventilated patients between February 2020 and December 2021. We examined the association between mechanical power and its components (elastic static, elastic dynamic, total elastic"],"journal":["Annals of intensive care"],"pubmed_title":["Mechanical power is not associated with mortality in COVID-19 mechanically ventilated patients."],"pmcid":["PMC11861844"],"funding_grant_id":["ISCIII","(ISCIII","Sara Borrell 2021: CD21/00087","Miguel Servet 2020: CP20/00041","COV20/00110"],"pubmed_authors":["Moral-Parras P","Adell-Serrano B","Sancho S","Bastida LP","Val E","Trefler S","Furro A","Leon M","Ferrer R","Climent C","Ferrando C","Planelles GP","Mantellini CL","Peis EM","Blancas R","Hermoso DC","Cachafeiro L","Pous AP","Gonzalez J","Ocon M","Riera J","Badia M","Bueno L","Nieto MT","Roche-Campo F","Gracia MP","Jimenez JFM","Fernandez-Barat L","Castellvi A","Gomez JM","Sarinena MT","Prados J","Arijon IE","Lago AL","Lopez J","Pravia OB","de Castro FR","Clar L","Rubio J","Fernandez EMM","Gonzalez CG","Ossa S","Pinol-Tena A","Ruiz CR","Martin MC","Agrifoglio A","Rubio EP","Tormos A","Cilloniz C","Trujillano J","Alvarez JIL","Van der Hofstadt Martin-Montalvo M","Barbera C","Servia L","Albaiceta GM","Kiarostami K","Bofill N","Bustamante-Munguira E","Cabello MA","Socias L","Bustamante-Munguira J","Warrington TV","Pujol A","Vilas MDR","Alcaraz-Serrano V","Vengoechea J","Tamayo L","Anon JM","Soliva L","Barreiros C","Moreno CD","Cano SGM","Coll NR","Delgado MCM","Espina LF","Maseda E","Ortega A","Lazaro AS","Trenado J","Montejo-Gonzalez JC","Valdivia LJ","Gumucio-Sanguino VD","Martinez I","Castillo MLG","Goma G","Barbeta E","Garcia F","Martinez M","Fernandez PC","Martinez A","Garcia B","Bardi T","Diaz MJ","Barberan J","Casal VG","Penuelas O","Alegre C","Sagredo V","Carbajales C","Sagastume AG","Urrelo-Cerron L","Caballero J","Codina J","Carvalho S","Ibarz M","Loza-Vazquez A","Bigas J","Alvarez S","Garcia RNJ","Dot I","Perez P","Gordo F","Speziale C","Forcadell-Ferreres E","Forin E","Franco N","Arrieta M","Pagliarani P","Fernandez SC","Barbena L","Adrio SV","Tognetti D","Lorente JA","Cano I","Gomez S","Vicente PM","Aznar MM","Garcia LC","Contreras S","Herran-Monge R","Balsera B","Estella A","Giraudo PE","Castro P","Salinas RN","Mendiluce RM","Sanchez M","Avila RC","Penasco Y","de Gonzalo-Calvo D","Degracia AS","Del Busto Martinez C","Herrera NM","Ruiz LV","Vidal J","Vieiro MTB","Conde P","Vidal P","Gallego E","Torres M","Sole-Violan J","Bou RN","de la Torre MDC","Barbe F","Boado MV","Novo MA","Herraiz A","Serra-Fortuny M","Perez-Garcia F","Torres A","Monclou J","Marcos P","Garcia JAB","Cortes PV","Sanchez-Giron GR","Cortes MLB","Fernandez J","Badia JR","Miralles MR","Ricart P","Rodriguez DM","Prieto EG","Sanchez A","Balan A","Segade PB","Amaya-Villar R","Sanchez-Miralles A","Nicolas JM","Vila-Vilardel C","Aldecoa C","Carbonell N","Morales D","Ruiz AA","Monjo TF","Naya GM","Huerta A","Galban C","Laguna DP","Marin-Corral J","Santacoloma B","CIBERESUCICOVID Project investigators (COV20/00110, ISCIII)","Figueras A","Montserrat N","Redruello CG","Yang H","Lopez-Gavin A","Serra L","Guzzardella A","Yang M","Diaz Y","Barroso M","Casacuberta-Barbera N","Janer MT","Parrilla F","Catalan-Gonzalez M","Zapatero A","Iglesias S","Murua PR","Castella M","Motos A","Paz ES","Gabarrus A","Diaz E","Juan MDM","Rodriguez L","Vallverdu M","Guerrero DM","Saera MB","Vallverdu J","Boado M","Canton-Bulnes ML","Rodriguez A","Angel J","de Pablo Sanchez R","Ayestaran JI","Fernandez CEM","Blandino A","Rodriguez S","Ubeda A","Andrea R","Ceccato A","Vilanova J","Munoz-Bermudez R","De Mendoza D","Vazquez N","Pensado MS","Jimenez G","Masclans JR","Miralbes M","Aguilera L","Lopez AR"],"additional_accession":[]},"is_claimable":false,"name":"Mechanical power is not associated with mortality in COVID-19 mechanically ventilated patients.","description":"<h4>Background</h4>The relative contribution of the different components of mechanical power to mortality is a subject of debate and has not been studied in COVID-19. The aim of this study is to evaluate both the total and the relative impact of each of the components of mechanical power on mortality in a well-characterized cohort of patients with COVID-19-induced acute respiratory failure undergoing invasive mechanical ventilation. This is a secondary analysis of the CIBERESUCICOVID project, a multicenter observational cohort study including fifty Spanish intensive care units that included COVID-19 mechanically ventilated patients between February 2020 and December 2021. We examined the association between mechanical power and its components (elastic static, elastic dynamic, total elastic","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2026-07-15T08:45:15.529Z","creation":"2026-07-01T03:12:33.318Z"},"accession":"S-EPMC11861844","cross_references":{"pubmed":["39998751"],"doi":["10.1186/s13613-025-01430-6"]}}