{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(2)"],"submitter":["Omes C"],"pubmed_abstract":["Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections in all genders worldwide. Its association with male infertility is deeply investigated, although there are conflicting data on the role of the virus in the impairment of semen quality and reduced reproductive outcomes. In this study, we considered 335 semen samples of males (age: 37.63 ± 6.02 years) belonging to infertile couples who did not conceive a pregnancy after 12 months of unprotected intercourse. Residual semen samples, after routine sperm analysis, were used to amplify and type viral DNA. Positive or negative HPV semen samples were compared. In total, 42.51% (139/327) were positive for at least one HPV genotype, and in 54.68% (76/139), positivity was due to a high-risk (HR) genotype. Th"],"journal":["Tropical medicine and infectious disease"],"pagination":["36"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11861865"],"repository":["biostudies-literature"],"pubmed_title":["HPV-51 or HPV-52 Infection Could Impair Sperm Quality in Infertile Patients: A Preliminary Study on Our Experience from North-Western Italy."],"pmcid":["PMC11861865"],"pubmed_authors":["Omes C","Rienzi M","Piccinino M","Rossini R","Nappi RE"],"additional_accession":[]},"is_claimable":false,"name":"HPV-51 or HPV-52 Infection Could Impair Sperm Quality in Infertile Patients: A Preliminary Study on Our Experience from North-Western Italy.","description":"Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections in all genders worldwide. Its association with male infertility is deeply investigated, although there are conflicting data on the role of the virus in the impairment of semen quality and reduced reproductive outcomes. In this study, we considered 335 semen samples of males (age: 37.63 ± 6.02 years) belonging to infertile couples who did not conceive a pregnancy after 12 months of unprotected intercourse. Residual semen samples, after routine sperm analysis, were used to amplify and type viral DNA. Positive or negative HPV semen samples were compared. In total, 42.51% (139/327) were positive for at least one HPV genotype, and in 54.68% (76/139), positivity was due to a high-risk (HR) genotype. Th","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2025-04-03T23:43:06.462Z","creation":"2025-04-03T23:43:06.462Z"},"accession":"S-EPMC11861865","cross_references":{"pubmed":["39998040"],"doi":["10.3390/tropicalmed10020036"]}}