{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["4(1)"],"submitter":["Chen M"],"pubmed_abstract":["In metabarcoding research, such as taxon identification, phylogenetic placement plays a critical role. However, many existing phylogenetic placement methods lack comprehensive features for downstream analysis and visualization. Visualization tools often ignore placement uncertainty, making it difficult to explore and interpret placement data effectively. To overcome these limitations, we introduce a scalable approach using <i>treeio</i> and <i>ggtree</i> for parsing and visualizing phylogenetic placement data. The <i>treeio</i>-<i>ggtree</i> method supports placement filtration, uncertainty exploration, and customized visualization. It enhances scalability for large analyses by enabling users to extract subtrees from the full reference tree, focusing on specific samples within a clade. Additionally, this approach provides a clearer representation of phylogenetic placement uncertainty by visualizing associated placement information on the final placement tree."],"journal":["iMeta"],"pagination":["e269"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11865327"],"repository":["biostudies-literature"],"pubmed_title":["Scalable method for exploring phylogenetic placement uncertainty with custom visualizations using <i>treeio</i> and <i>ggtree</i>."],"pmcid":["PMC11865327"],"pubmed_authors":["Liao Y","Li J","Liang W","Chen M","Xie Z","Mo K","Yu G","Li L","Lam TT","Wang Q","Song Q","Xu S","Liu B","Luo X","Chen X"],"additional_accession":[]},"is_claimable":false,"name":"Scalable method for exploring phylogenetic placement uncertainty with custom visualizations using <i>treeio</i> and <i>ggtree</i>.","description":"In metabarcoding research, such as taxon identification, phylogenetic placement plays a critical role. However, many existing phylogenetic placement methods lack comprehensive features for downstream analysis and visualization. Visualization tools often ignore placement uncertainty, making it difficult to explore and interpret placement data effectively. To overcome these limitations, we introduce a scalable approach using <i>treeio</i> and <i>ggtree</i> for parsing and visualizing phylogenetic placement data. The <i>treeio</i>-<i>ggtree</i> method supports placement filtration, uncertainty exploration, and customized visualization. It enhances scalability for large analyses by enabling users to extract subtrees from the full reference tree, focusing on specific samples within a clade. Additionally, this approach provides a clearer representation of phylogenetic placement uncertainty by visualizing associated placement information on the final placement tree.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2025-04-03T23:13:54.877Z","creation":"2025-04-03T23:13:54.877Z"},"accession":"S-EPMC11865327","cross_references":{"pubmed":["40027482"],"doi":["10.1002/imt2.269"]}}