biostudies-literatureUnknown25(1)Ali MM<h4>Background</h4>Neonatal sepsis is a significant cause of morbidity and mortality in low- income countries. Neonatal sepsis is classified as early-onset neonatal sepsis (EONS) and late-onset neonatal sepsis (LONS). Etiologies responsible for EONS are mostly acquired vertically from the mother during or before birth with the possibility of prevention. The burden and etiology of neonatal sepsis is not uniform across the globe with huge disparities based on the income level of the countries. This study aimed to determine neonatal sepsis trends, prevalence, and etiologies at Hawassa University Comprehensive Specialised Hospital (HUCSH).<h4>Methods</h4>A hospital-based retrospective cross-sectional study was conducted among newborns aged 0 to 90 days who were admitted to the HUCSH from JanuaBMC pediatrics152https://www.ebi.ac.uk/biostudies/studies/S-EPMC11869412biostudies-literatureTrends of neonatal sepsis and its etiology at Hawassa, Ethiopia: a five year retrospective cross-sectional study.PMC11869412Kijineh BReda DYMengistu MWorku EFenta DALambiyo THailemeriam TKwatra GAli MMAlemayehu TfalseTrends of neonatal sepsis and its etiology at Hawassa, Ethiopia: a five year retrospective cross-sectional study.<h4>Background</h4>Neonatal sepsis is a significant cause of morbidity and mortality in low- income countries. Neonatal sepsis is classified as early-onset neonatal sepsis (EONS) and late-onset neonatal sepsis (LONS). Etiologies responsible for EONS are mostly acquired vertically from the mother during or before birth with the possibility of prevention. The burden and etiology of neonatal sepsis is not uniform across the globe with huge disparities based on the income level of the countries. This study aimed to determine neonatal sepsis trends, prevalence, and etiologies at Hawassa University Comprehensive Specialised Hospital (HUCSH).<h4>Methods</h4>A hospital-based retrospective cross-sectional study was conducted among newborns aged 0 to 90 days who were admitted to the HUCSH from Janua2025-01-01T00:00:00Z2025 Feb2025-04-05T14:38:34.995Z2025-04-05T14:38:34.995ZS-EPMC118694124002203210.1186/s12887-025-05515-w