{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["24"],"submitter":["Ali E"],"pubmed_abstract":["<h4>Introduction</h4>Lung cancer remains the leading cause of cancer-related mortality in the United States and shares cardiovascular risk factors with chronic ischemic heart disease (CIHD). However, the cumulative mortality burden of these comorbid conditions is underexplored. This study aims to retrospectively assess mortality trends among American adults with concurrent lung cancer and CIHD.<h4>Methods</h4>We utilized death certificate data from the Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) database, encompassing ICD-10 codes for individuals aged ≥45 years from 1999 to 2020. Age-adjusted mortality rates (AAMRs) per 100,000 population, annual percentage change (APC), and corresponding 95 % confidence intervals (CIs) were"],"journal":["International journal of cardiology. Cardiovascular risk and prevention"],"pagination":["200377"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11875809"],"repository":["biostudies-literature"],"pubmed_title":["Trends and regional variations in chronic ischemic heart disease and lung cancer-related mortality among American adults: Insights from retrospective CDC wonder analysis."],"pmcid":["PMC11875809"],"pubmed_authors":["Ali Fahim MA","Ali E","Ur Rahman HA","Alkhas C","Khan HN","Salman A","Shaik AA","Kamal UH","Salman M","Yasmin F","Asghar MS","Alraies MC"],"additional_accession":[]},"is_claimable":false,"name":"Trends and regional variations in chronic ischemic heart disease and lung cancer-related mortality among American adults: Insights from retrospective CDC wonder analysis.","description":"<h4>Introduction</h4>Lung cancer remains the leading cause of cancer-related mortality in the United States and shares cardiovascular risk factors with chronic ischemic heart disease (CIHD). However, the cumulative mortality burden of these comorbid conditions is underexplored. This study aims to retrospectively assess mortality trends among American adults with concurrent lung cancer and CIHD.<h4>Methods</h4>We utilized death certificate data from the Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) database, encompassing ICD-10 codes for individuals aged ≥45 years from 1999 to 2020. Age-adjusted mortality rates (AAMRs) per 100,000 population, annual percentage change (APC), and corresponding 95 % confidence intervals (CIs) were","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-04-03T23:32:45.14Z","creation":"2025-04-03T23:32:45.14Z"},"accession":"S-EPMC11875809","cross_references":{"pubmed":["40034236"],"doi":["10.1016/j.ijcrp.2025.200377"]}}