{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(2)"],"submitter":["Hanai Y"],"pubmed_abstract":["<h4>Background</h4>Appropriate antibiotic prophylaxis is essential for preventing surgical site infections (SSI); however, the clinical benefit of intraoperative redosing remains unclear and controversial owing to insufficient reliable evidence. Therefore, we performed a systematic review and meta-analysis to assess the effectiveness of prophylactic antibiotic redosing in lengthy surgical procedures.<h4>Methods</h4>We systematically searched the PubMed, Cochrane Library, Web of Science, and Ichushi-Web databases for articles published until 31 December, 2023. We compared the incidence of SSI between patients receiving and not receiving intraoperative redosing of antibiotics in surgeries lasting ≥3 h. Subgroup analyses were conducted across study characteristics. Odds ratios (ORs) and 95% c"],"journal":["Annals of gastroenterological surgery"],"pagination":["369-378"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11877348"],"repository":["biostudies-literature"],"pubmed_title":["Intraoperative redosing of antibiotics for prevention of surgical site infections: A systematic review and meta-analysis."],"pmcid":["PMC11877348"],"pubmed_authors":["Yoshida M","Hirai J","Kitagawa Y","Yamashita C","Ohge H","Shinkawa H","Suzuki K","Kobayashi M","Matsuo K","Shimizu J","Mohri Y","Haji S","Mizuguchi T","Kouzu K","Hanai Y","Mayumi T","Nobuhara H","Shinji S","Uchino M"],"additional_accession":[]},"is_claimable":false,"name":"Intraoperative redosing of antibiotics for prevention of surgical site infections: A systematic review and meta-analysis.","description":"<h4>Background</h4>Appropriate antibiotic prophylaxis is essential for preventing surgical site infections (SSI); however, the clinical benefit of intraoperative redosing remains unclear and controversial owing to insufficient reliable evidence. Therefore, we performed a systematic review and meta-analysis to assess the effectiveness of prophylactic antibiotic redosing in lengthy surgical procedures.<h4>Methods</h4>We systematically searched the PubMed, Cochrane Library, Web of Science, and Ichushi-Web databases for articles published until 31 December, 2023. We compared the incidence of SSI between patients receiving and not receiving intraoperative redosing of antibiotics in surgeries lasting ≥3 h. Subgroup analyses were conducted across study characteristics. Odds ratios (ORs) and 95% c","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-04-05T14:30:44.693Z","creation":"2025-04-05T14:30:44.693Z"},"accession":"S-EPMC11877348","cross_references":{"pubmed":["40046532"],"doi":["10.1002/ags3.12866"]}}