{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(Suppl 3)"],"submitter":["Atuhaire P"],"pubmed_abstract":["<h4>Background</h4>Low- and middle-income countries lack data on culture-confirmed sepsis in HIV-exposed infants, despite the reported heightened risk of infectious morbidity. This study describes culture-confirmed sepsis and antibiotic resistance patterns among HIV-exposed children in a large etiological cohort study in Kampala, Uganda.<h4>Methods</h4>This was a prospective birth cohort study based at 2 Ugandan sites, as part of the Progressing Group B Streptococcal Vaccines (PROGRESS) study. Any infant with risk factors, signs, or symptoms of infection presenting before 3 months of age had a blood culture and nasopharyngeal swab taken to determine the etiology of neonatal and young infant sepsis.<h4>Results</h4>Among 4492 blood cultures, 460 were obtained from HIV-exposed infants. Nine i"],"journal":["Open forum infectious diseases"],"pagination":["S187-S192"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11891132"],"repository":["biostudies-literature"],"pubmed_title":["HIV Exposure and Neonatal Sepsis: A Descriptive Etiological Study."],"pmcid":["PMC11891132"],"pubmed_authors":["Doare KL","Kipyeko S","Najuka C","Beach S","Heath PT","Cochet M","PROGRESS Study Author Group","Tusubira V","Portal EAR","O'Hara G","Wamawobe A","Seeley J","Davies HG","Azuba R","Djennad A","Komugisha C","Mutabazi T","Le Doare K","Karampatsas K","Ravji P","Nakimuli A","Shelley DR","Namugumya R","Musoke P","Spiller OB","Ssali A","Karafillakis E","Farley C","Nyamaizi A","Owor M","Nanyunja C","Peacock J","Cowie K","Sewegaba M","Chalker V","Katungye R","Voysey M","Sekikubo M","Etti M","Matovu G","Sendagala JN","Nalubega P","Parks R","Duckworth E","Atuhaire P","Hookham L","Old T","Kyohere M","Bentley S","Amone A","Musooko M"],"additional_accession":[]},"is_claimable":false,"name":"HIV Exposure and Neonatal Sepsis: A Descriptive Etiological Study.","description":"<h4>Background</h4>Low- and middle-income countries lack data on culture-confirmed sepsis in HIV-exposed infants, despite the reported heightened risk of infectious morbidity. This study describes culture-confirmed sepsis and antibiotic resistance patterns among HIV-exposed children in a large etiological cohort study in Kampala, Uganda.<h4>Methods</h4>This was a prospective birth cohort study based at 2 Ugandan sites, as part of the Progressing Group B Streptococcal Vaccines (PROGRESS) study. Any infant with risk factors, signs, or symptoms of infection presenting before 3 months of age had a blood culture and nasopharyngeal swab taken to determine the etiology of neonatal and young infant sepsis.<h4>Results</h4>Among 4492 blood cultures, 460 were obtained from HIV-exposed infants. Nine i","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-05-29T16:50:53.395Z","creation":"2025-04-07T07:56:38.688Z"},"accession":"S-EPMC11891132","cross_references":{"pubmed":["40070699"],"doi":["10.1093/ofid/ofae642"]}}