{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(11)"],"submitter":["Huang M"],"funding":["Fujian Provincial Health Technology Project","Natural Science Foundation of Fujian Province"],"pubmed_abstract":["Shigellosis is a serious public health issue in many developing countries. The emergence of multidrug-resistant (MDR) <i>Shigella</i> isolates has deepened the treatment difficulty and health burden of shigellosis. China is the largest developing country in the world, but so far, the genome of MDR <i>Shigella</i> isolates has not been well characterized. In this study, 60 clinical isolates of <i>Shigella</i> spp. in Fujian Province, southeast China, from 2005 to 2019 were characterized for drug resistance phenotype, whole-genome sequencing and bioinformatics analysis. The results showed that the MDR rate of <i>Shigella</i> isolates was 100%, among which the resistance rates of cefotaxime, ciprofloxacin and azithromycin were 36.67, 21.67 and 10.00 %, respectively. The positive rate of exten"],"journal":["Microbial genomics"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11893363"],"repository":["biostudies-literature"],"pubmed_title":["Genome and antibiotic resistance characteristics of &lt;i&gt;Shigella&lt;/i&gt; clinical isolates in Fujian Province, Southeast China, 2005-2019."],"pmcid":["PMC11893363"],"funding_grant_id":["2022J01399","2021CXA024"],"pubmed_authors":["Qiu Y","Yang J","Zhang X","Huang M","Luo C","Xu H"],"additional_accession":[]},"is_claimable":false,"name":"Genome and antibiotic resistance characteristics of &lt;i&gt;Shigella&lt;/i&gt; clinical isolates in Fujian Province, Southeast China, 2005-2019.","description":"Shigellosis is a serious public health issue in many developing countries. The emergence of multidrug-resistant (MDR) <i>Shigella</i> isolates has deepened the treatment difficulty and health burden of shigellosis. China is the largest developing country in the world, but so far, the genome of MDR <i>Shigella</i> isolates has not been well characterized. In this study, 60 clinical isolates of <i>Shigella</i> spp. in Fujian Province, southeast China, from 2005 to 2019 were characterized for drug resistance phenotype, whole-genome sequencing and bioinformatics analysis. The results showed that the MDR rate of <i>Shigella</i> isolates was 100%, among which the resistance rates of cefotaxime, ciprofloxacin and azithromycin were 36.67, 21.67 and 10.00 %, respectively. The positive rate of exten","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-06-01T18:01:13.403Z","creation":"2025-04-04T00:21:26.87Z"},"accession":"S-EPMC11893363","cross_references":{"pubmed":["39565081"],"doi":["10.1099/mgen.0.001325"]}}