{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(1)"],"submitter":["Kim AR"],"pubmed_abstract":["<h4>Introduction</h4>Clinical trial evidence supports early low-density lipoprotein cholesterol (LDL-C) goal achievement in patients with atherosclerotic cardiovascular disease (ASCVD), but real-world evidence in Asia is lacking. We investigated the effects of early LDL-C goal achievement on recurrent major cardiovascular events (MACEs) among patients with very-high-risk ASCVD in South Korea.<h4>Methods</h4>We included adult patients hospitalized with ASCVD (acute coronary syndrome [ACS], stable angina, ischemic stroke, transient ischemic attack, peripheral arterial disease, or asymptomatic coronary artery disease) at a major Korean tertiary hospital from 2000 to 2020. Patients were categorized into early or non-early target LDL-C groups based on LDL-C measured 4-12 weeks post-discharge (<"],"journal":["Cardiology and therapy"],"pagination":["101-115"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11893916"],"repository":["biostudies-literature"],"pubmed_title":["Cardiovascular Outcomes of Early LDL-C Goal Achievement in Patients with Very-High-Risk ASCVD."],"pmcid":["PMC11893916"],"pubmed_authors":["Kang HJ","Kwon SU","Kwon O","Lee H","Baek YH","Kim M","Ahn I","Kim YH","Kim AR","Oh JS","Kim JH","Jun TJ","Han JY"],"additional_accession":[]},"is_claimable":false,"name":"Cardiovascular Outcomes of Early LDL-C Goal Achievement in Patients with Very-High-Risk ASCVD.","description":"<h4>Introduction</h4>Clinical trial evidence supports early low-density lipoprotein cholesterol (LDL-C) goal achievement in patients with atherosclerotic cardiovascular disease (ASCVD), but real-world evidence in Asia is lacking. We investigated the effects of early LDL-C goal achievement on recurrent major cardiovascular events (MACEs) among patients with very-high-risk ASCVD in South Korea.<h4>Methods</h4>We included adult patients hospitalized with ASCVD (acute coronary syndrome [ACS], stable angina, ischemic stroke, transient ischemic attack, peripheral arterial disease, or asymptomatic coronary artery disease) at a major Korean tertiary hospital from 2000 to 2020. Patients were categorized into early or non-early target LDL-C groups based on LDL-C measured 4-12 weeks post-discharge (<","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-04-22T11:19:51.333Z","creation":"2025-04-05T23:54:33.496Z"},"accession":"S-EPMC11893916","cross_references":{"pubmed":["39988704"],"doi":["10.1007/s40119-025-00397-6"]}}