{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6(6)"],"submitter":["Hu T"],"pubmed_abstract":["Q fever is a zoonotic disease caused by infection with <i>Coxiella burnetii</i> (<i>C. burnetii</i>). Due to its atypical symptoms and the absence of specific detection methods, Q fever is underdiagnosed commonly. Herein, we report a case of Q fever confirmed by metagenomic next-generation sequencing (mNGS) in March 2024 in Guangdong Province, China. The patient initially experienced fever and was admitted to hospital six days later. Despite a series of laboratory tests conducted at the hospital, the pathogen remained undetermined. Ten days after admission, mNGS revealed that the patient was infected with <i>C. burnetii</i>. The patient subsequently underwent treatment with doxycycline and recovered well. Epidemiological investigation revealed that the patient had been exposed to sheep inf"],"journal":["Biosafety and health"],"pagination":["337-340"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11895022"],"repository":["biostudies-literature"],"pubmed_title":["Q fever diagnosed using metagenomic next-generation sequencing in Guangdong Province, China."],"pmcid":["PMC11895022"],"pubmed_authors":["Zhou M","Hu T","Zhang M","Cheng Y","Zhuang Y","Liu Y","Li X","Wang P","Tan X","Zhang X","Deng A","Wan J","Cheng L","Kang M","Zong J"],"additional_accession":[]},"is_claimable":false,"name":"Q fever diagnosed using metagenomic next-generation sequencing in Guangdong Province, China.","description":"Q fever is a zoonotic disease caused by infection with <i>Coxiella burnetii</i> (<i>C. burnetii</i>). Due to its atypical symptoms and the absence of specific detection methods, Q fever is underdiagnosed commonly. Herein, we report a case of Q fever confirmed by metagenomic next-generation sequencing (mNGS) in March 2024 in Guangdong Province, China. The patient initially experienced fever and was admitted to hospital six days later. Despite a series of laboratory tests conducted at the hospital, the pathogen remained undetermined. Ten days after admission, mNGS revealed that the patient was infected with <i>C. burnetii</i>. The patient subsequently underwent treatment with doxycycline and recovered well. Epidemiological investigation revealed that the patient had been exposed to sheep inf","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2025-04-04T02:54:20.478Z","creation":"2025-04-04T02:54:20.478Z"},"accession":"S-EPMC11895022","cross_references":{"pubmed":["40078981"],"doi":["10.1016/j.bsheal.2024.11.003"]}}