{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Koch V"],"funding":["Agence Nationale de la Recherche","Doktor Robert Pfleger-Stiftung","SiRIC InsiTu: Insights into cancer: From inflammation to tumor"],"pagination":["1890-1904"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11896941"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["61(4)"],"pubmed_abstract":["<h4>Background</h4>Magnetic resonance elastography (MRE) can quantify tissue biomechanics noninvasively, including pathological hepatic states like metabolic dysfunction-associated steatohepatitis.<h4>Purpose</h4>To compare the performance of 2D/3D-MRE using the gravitational (GT) transducer concept with the current commercial acoustic (AC) solution utilizing a 2D-MRE approach. Additionally, quality index markers (QIs) were proposed to identify image pixels with sufficient quality for reliably estimating tissue biomechanics.<h4>Study type</h4>Prospective.<h4>Population</h4>One hundred seventy participants with suspected or confirmed liver disease (median age, 57 years [interquartile range (IQR), 46-65]; 66 females), and 11 healthy volunteers (median age, 31 years [IQR, 27-34]; 5 females).<"],"journal":["Journal of magnetic resonance imaging : JMRI"],"pubmed_title":["Biomechanical Assessment of Liver Integrity: Prospective Evaluation of Mechanical Versus Acoustic MR Elastography."],"pmcid":["PMC11896941"],"funding_grant_id":["INCa-DGOS-INSERM-ITMO Cancer_18008","ANR-21-RHUS-0012"],"pubmed_authors":["Finkelmeier F","Ziegengeist NS","Cengiz D","Vogl TJ","Mahmoudi S","Zeuzem S","D'Angelo T","Pathil-Warth A","Booz C","Hammerstingl RM","Dahmer I","Kinzler MN","Cimprich M","Almansour H","Eichler K","Koch V","Scholtz JE","Solim LA","Gotta J","Martin SS","Bernatz S","Darwish O","Gruenewald LD","Torgashov K","Annio G","Herrmann E","Thalhammer A","Alizadeh LS","Onay M","Konrad P","Chernyak V","Wild P","Vilgrain V","Yel I","Sinkus R","Gruber-Rouh T","Taylor SA"],"additional_accession":[]},"is_claimable":false,"name":"Biomechanical Assessment of Liver Integrity: Prospective Evaluation of Mechanical Versus Acoustic MR Elastography.","description":"<h4>Background</h4>Magnetic resonance elastography (MRE) can quantify tissue biomechanics noninvasively, including pathological hepatic states like metabolic dysfunction-associated steatohepatitis.<h4>Purpose</h4>To compare the performance of 2D/3D-MRE using the gravitational (GT) transducer concept with the current commercial acoustic (AC) solution utilizing a 2D-MRE approach. Additionally, quality index markers (QIs) were proposed to identify image pixels with sufficient quality for reliably estimating tissue biomechanics.<h4>Study type</h4>Prospective.<h4>Population</h4>One hundred seventy participants with suspected or confirmed liver disease (median age, 57 years [interquartile range (IQR), 46-65]; 66 females), and 11 healthy volunteers (median age, 31 years [IQR, 27-34]; 5 females).<","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-04-04T00:27:35.857Z","creation":"2025-04-04T00:27:35.857Z"},"accession":"S-EPMC11896941","cross_references":{"pubmed":["39165139"],"doi":["10.1002/jmri.29560"]}}