{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["19"],"submitter":["Smallwood N"],"funding":["Fisher and Paykel Healthcare"],"pubmed_abstract":["<h4>Background</h4>High-flow nasal oxygen (HFNO) therapy delivers humidified, heated air with flow rates of up to 60 L/min with oxygen entrained. HFNO has advantages over conventional oxygen therapy, including precise and reliable fraction of inspired oxygen delivery, therefore is recommended as first-line treatment for people with acute hypoxaemic respiratory failure.<h4>Objectives</h4>This pilot study aimed to determine the feasibility and acceptability of domiciliary nasal high flow (NHF) without entrained oxygen for people with chronic obstructive pulmonary disease (COPD) and severe breathlessness.<h4>Design</h4>Single-arm, mixed-methods, pilot study of an 8-day, air-only NHF intervention in adults with COPD and severe breathlessness not requiring domiciliary oxygen therapy.<h4>Methods"],"journal":["Therapeutic advances in respiratory disease"],"pagination":["17534666251314722"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11898029"],"repository":["biostudies-literature"],"pubmed_title":["A mixed-methods pilot study of domiciliary nasal high-flow therapy for breathlessness in people with chronic obstructive pulmonary disease who do not qualify for domiciliary long-term oxygen therapy."],"pmcid":["PMC11898029"],"pubmed_authors":["Currow D","Buchan C","Pascoe A","Smallwood N","Wong AK","Le B"],"additional_accession":[]},"is_claimable":false,"name":"A mixed-methods pilot study of domiciliary nasal high-flow therapy for breathlessness in people with chronic obstructive pulmonary disease who do not qualify for domiciliary long-term oxygen therapy.","description":"<h4>Background</h4>High-flow nasal oxygen (HFNO) therapy delivers humidified, heated air with flow rates of up to 60 L/min with oxygen entrained. HFNO has advantages over conventional oxygen therapy, including precise and reliable fraction of inspired oxygen delivery, therefore is recommended as first-line treatment for people with acute hypoxaemic respiratory failure.<h4>Objectives</h4>This pilot study aimed to determine the feasibility and acceptability of domiciliary nasal high flow (NHF) without entrained oxygen for people with chronic obstructive pulmonary disease (COPD) and severe breathlessness.<h4>Design</h4>Single-arm, mixed-methods, pilot study of an 8-day, air-only NHF intervention in adults with COPD and severe breathlessness not requiring domiciliary oxygen therapy.<h4>Methods","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan-Dec","modification":"2025-04-04T09:07:19.338Z","creation":"2025-04-04T09:07:19.338Z"},"accession":"S-EPMC11898029","cross_references":{"pubmed":["40071312"],"doi":["10.1177/17534666251314722"]}}