{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ricardo J"],"funding":["IBEROS+"],"pagination":["630"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11902790"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(5)"],"pubmed_abstract":["This research presents a novel, cost-effective, and scalable approach for the direct detection of myoglobin (Myo) in point-of-care (PoC) applications. In this strategy, redox-active Prussian Blue nanocubes (PBNCs) are applied to a disposable platinum screen-printed electrode (Pt-SPE). Subsequently, a biomimetic sensing layer is generated by electropolymerization of ortho-phenylenediamine (o-PD) in the presence of Myo, which forms molecularly imprinted polymer (MIP) sites by cyclic voltammetry (CV). The electropolymerization process takes place in a potential range of -0.2 V to +0.8 V, for five cycles at a scan rate of 50 mV/s, in a 10 mmol/L o-PD solution. After polymerization, the electrode is incubated in trypsin for 2 h to create Myo-specifically imprinted cavities. The structural and m"],"journal":["Polymers"],"pubmed_title":["Biomimetic Prussian Blue Sensor for Ultrasensitive Direct Detection of Myoglobin."],"pmcid":["PMC11902790"],"funding_grant_id":["(0072_IBEROS_MAIS_1_E, Interreg-POCTEP 2021-2027"],"pubmed_authors":["Moreira FTC","Ricardo J","Chiussi S","Martins GV","Duarte A"],"additional_accession":[]},"is_claimable":false,"name":"Biomimetic Prussian Blue Sensor for Ultrasensitive Direct Detection of Myoglobin.","description":"This research presents a novel, cost-effective, and scalable approach for the direct detection of myoglobin (Myo) in point-of-care (PoC) applications. In this strategy, redox-active Prussian Blue nanocubes (PBNCs) are applied to a disposable platinum screen-printed electrode (Pt-SPE). Subsequently, a biomimetic sensing layer is generated by electropolymerization of ortho-phenylenediamine (o-PD) in the presence of Myo, which forms molecularly imprinted polymer (MIP) sites by cyclic voltammetry (CV). The electropolymerization process takes place in a potential range of -0.2 V to +0.8 V, for five cycles at a scan rate of 50 mV/s, in a 10 mmol/L o-PD solution. After polymerization, the electrode is incubated in trypsin for 2 h to create Myo-specifically imprinted cavities. The structural and m","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2025-04-04T09:07:43.852Z","creation":"2025-04-04T09:07:43.852Z"},"accession":"S-EPMC11902790","cross_references":{"pubmed":["40076122"],"doi":["10.3390/polym17050630"]}}