{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["51(1)"],"submitter":["Glynn R"],"pubmed_abstract":["<h4>Purpose</h4>Major trauma is a leading cause of acute morbidity and mortality. While injury severity drives much of the associated burden, pre-existing comorbidities may influence both acute management and long-term outcomes. This scoping review examines the impact of comorbidities on trauma outcomes.<h4>Methods</h4>Embase, Medline, CINAHL, Cochrane Library, and PubMed were systematically searched from inception to 22/04/2021 (update 22/03/2024). Studies investigating comorbidities as risk factors for adverse outcomes in adults (≥ 18 years) with major trauma were included.<h4>Results</h4>Of 5448 studies identified, 33 met inclusion criteria. No studies examined whether comorbidities increases the risk of major trauma, and only two studies investigated the development of comorbidities po"],"journal":["European journal of trauma and emergency surgery : official publication of the European Trauma Society"],"pagination":["133"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11903538"],"repository":["biostudies-literature"],"pubmed_title":["Major trauma and comorbidity: a scoping review."],"pmcid":["PMC11903538"],"pubmed_authors":["Glynn R","Edwards F","Laupland KB","Gardiner B","Wullschleger M"],"additional_accession":[]},"is_claimable":false,"name":"Major trauma and comorbidity: a scoping review.","description":"<h4>Purpose</h4>Major trauma is a leading cause of acute morbidity and mortality. While injury severity drives much of the associated burden, pre-existing comorbidities may influence both acute management and long-term outcomes. This scoping review examines the impact of comorbidities on trauma outcomes.<h4>Methods</h4>Embase, Medline, CINAHL, Cochrane Library, and PubMed were systematically searched from inception to 22/04/2021 (update 22/03/2024). Studies investigating comorbidities as risk factors for adverse outcomes in adults (≥ 18 years) with major trauma were included.<h4>Results</h4>Of 5448 studies identified, 33 met inclusion criteria. No studies examined whether comorbidities increases the risk of major trauma, and only two studies investigated the development of comorbidities po","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-04-03T23:23:53.366Z","creation":"2025-04-03T23:23:53.366Z"},"accession":"S-EPMC11903538","cross_references":{"pubmed":["40074872"],"doi":["10.1007/s00068-025-02805-x"]}}