{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(3)"],"submitter":["Trieu HT"],"funding":["Wellcome Trust"],"pubmed_abstract":["<h4>Introduction</h4>The pathognomonic feature of dengue shock syndrome (DSS) is a transient capillary leak syndrome resulting in profound intravascular volume depletion. WHO management guidelines recommend particular parenteral fluid regimens during the critical leakage phase, including synthetic colloid solutions in certain circumstances. We set out to describe the actual fluid management strategies employed in different settings and to investigate relationships with clinical outcomes.<h4>Methods</h4>We performed a retrospective review of paediatric DSS cases managed at seven hospitals across Malaysia, Myanmar and Vietnam. We explored the effects of both initial resuscitation (crystalloid alone or mixed crystalloid/colloid in the first 2 hours) and general management: group 1 (conservati"],"journal":["BMJ global health"],"pagination":["e017538"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11904338"],"repository":["biostudies-literature"],"pubmed_title":["The influence of fluid resuscitation strategy on outcomes from dengue shock syndrome: a review of the management of 691 children in 7 Southeast Asian hospitals."],"pmcid":["PMC11904338"],"pubmed_authors":["Lwin YM","Bahtar AZ","Trieu HT","Phan TQ","See LLC","Ward N","Min EJ","Faridah Syed Omar S","Wai KZ","Nguyen TA","Vuong NL","Nguyen Van VC","Thi KS","Yacoub S","Ling HY","Nguyen Thi Truong A","Ling SCH","Nguyen Thi Minh S","Lam PK","Nachiappan N","Trinh H","Hung NT","Ramakrishnan A","Wills B","Nguyen Minh T","Ling AJ","Seng LE","Voon HK","Ward A"],"additional_accession":[]},"is_claimable":false,"name":"The influence of fluid resuscitation strategy on outcomes from dengue shock syndrome: a review of the management of 691 children in 7 Southeast Asian hospitals.","description":"<h4>Introduction</h4>The pathognomonic feature of dengue shock syndrome (DSS) is a transient capillary leak syndrome resulting in profound intravascular volume depletion. WHO management guidelines recommend particular parenteral fluid regimens during the critical leakage phase, including synthetic colloid solutions in certain circumstances. We set out to describe the actual fluid management strategies employed in different settings and to investigate relationships with clinical outcomes.<h4>Methods</h4>We performed a retrospective review of paediatric DSS cases managed at seven hospitals across Malaysia, Myanmar and Vietnam. We explored the effects of both initial resuscitation (crystalloid alone or mixed crystalloid/colloid in the first 2 hours) and general management: group 1 (conservati","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-04-22T07:22:21.083Z","creation":"2025-04-05T22:06:05.53Z"},"accession":"S-EPMC11904338","cross_references":{"pubmed":["40068930"],"doi":["10.1136/bmjgh-2024-017538"]}}