{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Cruz AK"],"funding":["NCCIH NIH HHS","NIDDK NIH HHS","NIA NIH HHS","NIEHS NIH HHS","NCI NIH HHS"],"pagination":["125"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11904883"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(6)"],"pubmed_abstract":["<h4>Introduction</h4>Human metabolomics has made significant strides in understanding metabolic changes and their implications for human health, with promising applications in diagnostics and treatment, particularly regarding the gut microbiome. However, progress is hampered by issues with data comparability and reproducibility across studies, limiting the translation of these discoveries into practical applications.<h4>Objectives</h4>This study aims to evaluate the fit-for-purpose of a suite of human stool samples as potential candidate reference materials (RMs) and assess the state of the field regarding harmonizing gut metabolomics measurements.<h4>Methods</h4>An interlaboratory study was conducted with 18 participating institutions. The study allowed for the use of preferred analytical"],"journal":["Metabolomics : Official journal of the Metabolomic Society"],"pubmed_title":["Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors."],"pmcid":["PMC11904883"],"funding_grant_id":["P30 DK056350","R01 AT010271","U2C ES030857","U2C ES030170","U19 AG063744","U24 CA268153","P30 DK040561","U24 DK133658"],"pubmed_authors":["Dallmann G","Trejo JB","Zhang L","Meikopoulos T","Couvillion SP","Van Meulebroek L","Burnet MC","Bayless AL","Shen T","Jean-Francois F","Nam SL","Neto FC","Gika H","Pham TH","Cruz AK","Deik AA","Vanhaecke L","Bloodsworth KJ","Metz TO","Krakstrom M","Li Y","Meehan MJ","Carrillo KST","Rushing B","Dailey L","Flores R","Sumner S","Panitchpakdi M","Weldon KC","Da Silva S","Wishart DS","Eder JG","Clish CB","Hagiwara KA","Cumeras R","Davis WC","Dickens AM","Zheng J","Choy A","Servetas S","Munoz N","Oresic M","Virgiliou C","Mandal R","de la Mata AP","Schock T","Andresson T","Mouskeftara T","Lamichhane S","Raftery D","Bowden JA","Aristizabal-Henao JJ","Seifried H","Dorrestein PC","Bullock K","Gowda GAN","Pierre-Hugues S","Thibaut D","Alves MA","Fiehn O","Djukovic D","Harynuk JJ","Hoyt DW","Kyle JE","Kumar A"],"additional_accession":[]},"is_claimable":false,"name":"Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors.","description":"<h4>Introduction</h4>Human metabolomics has made significant strides in understanding metabolic changes and their implications for human health, with promising applications in diagnostics and treatment, particularly regarding the gut microbiome. However, progress is hampered by issues with data comparability and reproducibility across studies, limiting the translation of these discoveries into practical applications.<h4>Objectives</h4>This study aims to evaluate the fit-for-purpose of a suite of human stool samples as potential candidate reference materials (RMs) and assess the state of the field regarding harmonizing gut metabolomics measurements.<h4>Methods</h4>An interlaboratory study was conducted with 18 participating institutions. The study allowed for the use of preferred analytical","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-05-29T12:48:27.042Z","creation":"2025-04-03T23:26:38.636Z"},"accession":"S-EPMC11904883","cross_references":{"pubmed":["39495321"],"doi":["10.1007/s11306-024-02185-0"]}}