biostudies-literatureUnknown15Zhang J<h4>Objective</h4>An effective model for risk stratification and prognostic assessment of early hepatocellular carcinoma (HCC) patients following microwave ablation (MWA) is lacking in clinical practice. The aim of this study is to develop and validate a prognostic model specifically for these patients.<h4>Methods</h4>Between January 2008 and December 2018, 345 treatment-naïve patients with HCC conforming to the Milan criteria who underwent MWA were enrolled and randomly assigned to the training (n=209) and validation (n=136) cohorts. The nomogram model was constructed based on the predictors assessed by the multivariate Cox proportional hazards model and validated. Predictive accuracy and discriminative ability were further evaluated and compared with other prognostic models.<h4>Results</Frontiers in oncology1486149https://www.ebi.ac.uk/biostudies/studies/S-EPMC11906293biostudies-literatureDevelopment and validation of a prognostic nomogram for early hepatocellular carcinoma treated with microwave ablation.PMC11906293Zhang JLi TGuo GHan YGuo CZhou XfalseDevelopment and validation of a prognostic nomogram for early hepatocellular carcinoma treated with microwave ablation.<h4>Objective</h4>An effective model for risk stratification and prognostic assessment of early hepatocellular carcinoma (HCC) patients following microwave ablation (MWA) is lacking in clinical practice. The aim of this study is to develop and validate a prognostic model specifically for these patients.<h4>Methods</h4>Between January 2008 and December 2018, 345 treatment-naïve patients with HCC conforming to the Milan criteria who underwent MWA were enrolled and randomly assigned to the training (n=209) and validation (n=136) cohorts. The nomogram model was constructed based on the predictors assessed by the multivariate Cox proportional hazards model and validated. Predictive accuracy and discriminative ability were further evaluated and compared with other prognostic models.<h4>Results</2025-01-01T00:00:00Z20252025-04-04T14:48:03.846Z2025-04-04T14:48:03.846ZS-EPMC119062934009401110.3389/fonc.2025.1486149