{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li B"],"funding":["Shanghai Shen Kang Hospital Development Center","Science and Technology Commission of Shanghai Municipality (Shanghai Municipal Science and Technology Commission)","National Natural Science Foundation of China (National Science Foundation of China)"],"pagination":["160"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11906877"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8(1)"],"pubmed_abstract":["A computer-aided detection (CAD) system for early esophagus carcinoma identification during endoscopy with narrow-band imaging (NBI) was evaluated in a large-scale, prospective, tandem, randomized controlled trial to assess its effectiveness. The study was registered at the Chinese Clinical Trial Registry (ChiCTR2100050654, 2021/09/01). Involving 3400 patients were randomly assigned to either routine (routine-first) or CAD-assisted (CAD-first) NBI endoscopy, followed by the other procedure, with targeted biopsies taken at the end of the second examination. The primary outcome was the diagnosis of 1 or more neoplastic lesion of esophagus during the first examination. The CAD-first group demonstrated a significantly higher neoplastic lesion detection rate (3.12%) compared to the routine-firs"],"journal":["NPJ digital medicine"],"pubmed_title":["Effect of computer aided detection system on esophageal neoplasm diagnosis in varied levels of endoscopists."],"pmcid":["PMC11906877"],"funding_grant_id":["22XD1402200","SHDC2023CRT006","82273025","82203460"],"pubmed_authors":["Tan WM","Cai SL","Ren Z","Shi Q","Zhong YS","Cai MY","Li B","Qi ZP","Yan B","Du YY","He DL","Yu HH"],"additional_accession":[]},"is_claimable":false,"name":"Effect of computer aided detection system on esophageal neoplasm diagnosis in varied levels of endoscopists.","description":"A computer-aided detection (CAD) system for early esophagus carcinoma identification during endoscopy with narrow-band imaging (NBI) was evaluated in a large-scale, prospective, tandem, randomized controlled trial to assess its effectiveness. The study was registered at the Chinese Clinical Trial Registry (ChiCTR2100050654, 2021/09/01). Involving 3400 patients were randomly assigned to either routine (routine-first) or CAD-assisted (CAD-first) NBI endoscopy, followed by the other procedure, with targeted biopsies taken at the end of the second examination. The primary outcome was the diagnosis of 1 or more neoplastic lesion of esophagus during the first examination. The CAD-first group demonstrated a significantly higher neoplastic lesion detection rate (3.12%) compared to the routine-firs","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-04-26T08:44:37.538Z","creation":"2025-04-06T12:48:10.614Z"},"accession":"S-EPMC11906877","cross_references":{"pubmed":["40082585"],"doi":["10.1038/s41746-025-01532-2"]}}