biostudies-literatureUnknown4(4)Shibata K<h4>Background</h4>Transcatheter edge-to-edge repair (TEER) is used to treat patients with mitral regurgitation (MR). The Geriatric Nutritional Risk Index (GNRI) is a well-known nutritional marker that predicts mortality risk.<h4>Objectives</h4>The objectives of this study were to elucidate the clinical association between the degree of GNRI and different etiologies of MR and to clarify the patient samples for whom GNRI is more relevant to clinical outcomes following TEER.<h4>Methods</h4>Data from 3,554 patients with MR who underwent TEER were analyzed using a Japanese multicenter registry. The patients were classified into 4 groups: GNRI <82, GNRI 82 to 92, GNRI 92 to 98, and GNRI >98. Procedural and clinical outcomes were compared between GNRI groups. Short- and long-term all-cause mortaJACC. Advances101631https://www.ebi.ac.uk/biostudies/studies/S-EPMC11907445biostudies-literatureGeriatric Nutritional Risk Index Assessment in Patients Undergoing Transcatheter Edge-to-Edge Repair.PMC11907445Naganuma TKagase AHachinohe DShibata KOCEAN-Mitral InvestigatorsOhno YKubo SShirai SYamaguchi RMizuno SUeno HTokuda TYamaguchi JAmaki MOtsuka TShimura TNakashima MYamamoto MAsami MWatanabe YMizutani KIzumo MEnta YSaji MBota HHayashida KTsunamoto HKurita AKodama KYamawaki MfalseGeriatric Nutritional Risk Index Assessment in Patients Undergoing Transcatheter Edge-to-Edge Repair.<h4>Background</h4>Transcatheter edge-to-edge repair (TEER) is used to treat patients with mitral regurgitation (MR). The Geriatric Nutritional Risk Index (GNRI) is a well-known nutritional marker that predicts mortality risk.<h4>Objectives</h4>The objectives of this study were to elucidate the clinical association between the degree of GNRI and different etiologies of MR and to clarify the patient samples for whom GNRI is more relevant to clinical outcomes following TEER.<h4>Methods</h4>Data from 3,554 patients with MR who underwent TEER were analyzed using a Japanese multicenter registry. The patients were classified into 4 groups: GNRI <82, GNRI 82 to 92, GNRI 92 to 98, and GNRI >98. Procedural and clinical outcomes were compared between GNRI groups. Short- and long-term all-cause morta2025-01-01T00:00:00Z2025 Feb2025-04-04T00:08:30.36Z2025-04-04T00:08:30.36ZS-EPMC119074454001011210.1016/j.jacadv.2025.101631