biostudies-literatureChen GYoung Scientist Program of Beijing Stomatological Hospital, Capital Medical UniversityNational Natural Science Foundation of ChinaBeijing Municipal Administration of Hospitals Incubating ProgramCapital's Funds for Health Improvement and Research383https://www.ebi.ac.uk/biostudies/studies/S-EPMC11907896biostudies-literatureUnknown25(1)<h4>Background</h4>This study aimed to assess the prognosis of T1-2N0 stage tongue cancer patients who underwent surgery for the primary lesion without elective neck dissection and to identify the risk factors for prognosis.<h4>Methods</h4>We retrospectively analyzed early-stage tongue cancer patients in our center. Statistical analyses were performed using SPSS and R software.<h4>Results</h4>The study reviewed 168 patients, revealing a 3-year overall survival rate of 90.5%, a 3-year cervical lymph node metastasis-free survival rate of 73.2%, and a 3-year disease-specific survival rate of 89.3%. A depth of invasion of 3 mm showed significant prognostic value for overall survival (P = 0.001), cervical lymph node metastasis-free survival (P = 0.002), and disease-specific survival (P < 0.001)BMC oral healthNecessity of selective neck dissection for T1-2N0 TSCC patients: a retrospective cohort study.PMC11907896PX201905782370925YSP202310CFH2020-2-2143Feng ZChen GHan ZLi BKang JKong XfalseNecessity of selective neck dissection for T1-2N0 TSCC patients: a retrospective cohort study.<h4>Background</h4>This study aimed to assess the prognosis of T1-2N0 stage tongue cancer patients who underwent surgery for the primary lesion without elective neck dissection and to identify the risk factors for prognosis.<h4>Methods</h4>We retrospectively analyzed early-stage tongue cancer patients in our center. Statistical analyses were performed using SPSS and R software.<h4>Results</h4>The study reviewed 168 patients, revealing a 3-year overall survival rate of 90.5%, a 3-year cervical lymph node metastasis-free survival rate of 73.2%, and a 3-year disease-specific survival rate of 89.3%. A depth of invasion of 3 mm showed significant prognostic value for overall survival (P = 0.001), cervical lymph node metastasis-free survival (P = 0.002), and disease-specific survival (P < 0.001)2025-01-01T00:00:00Z2025 Mar2025-04-20T00:10:15.336Z2025-04-20T00:10:15.336ZS-EPMC119078964008291310.1186/s12903-025-05694-z