biostudies-literatureCaneva SMinistero della SaluteMinistero dell'Istruzione, dell'Università e della Ricercae16567https://www.ebi.ac.uk/biostudies/studies/S-EPMC11909009biostudies-literatureUnknown32(3)<h4>Background</h4>Idiopathic normal pressure hydrocephalus (iNPH) is a multifactorial progressive disease affecting cognition, gait, and urinary continence, potentially reversible, or at least improvable, by a prompt surgical intervention. Given its potential surgical improvement, it is crucial to determine who will benefit of a ventriculo-peritoneal shunt. To date, although several procedures are considered useful to diagnose iNPH, there is no agreement concerning the best timing of the clinical assessment or the role played by formal cognitive testing.<h4>Methods</h4>Thirty participants with suspected iNPH were assessed at baseline, 2, and 15 days after 24-h extended lumbar drainage (ELD). Timed Up and Go test (TUG), Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (MEuropean journal of neurologyBeyond early motor response: Longitudinal cognitive and gait assessments after extended lumbar drainage in normal pressure hydrocephalus.PMC11909009PE0000006ECS00000035Fiaschi PMori LBianconi APardini MCaneva SMerciadri PPesaresi AMarzi AHamedani MZona GPellegrino LfalseBeyond early motor response: Longitudinal cognitive and gait assessments after extended lumbar drainage in normal pressure hydrocephalus.<h4>Background</h4>Idiopathic normal pressure hydrocephalus (iNPH) is a multifactorial progressive disease affecting cognition, gait, and urinary continence, potentially reversible, or at least improvable, by a prompt surgical intervention. Given its potential surgical improvement, it is crucial to determine who will benefit of a ventriculo-peritoneal shunt. To date, although several procedures are considered useful to diagnose iNPH, there is no agreement concerning the best timing of the clinical assessment or the role played by formal cognitive testing.<h4>Methods</h4>Thirty participants with suspected iNPH were assessed at baseline, 2, and 15 days after 24-h extended lumbar drainage (ELD). Timed Up and Go test (TUG), Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (M2025-01-01T00:00:00Z2025 Mar2025-04-05T12:38:58.83Z2025-04-05T12:38:58.83ZS-EPMC119090094008784910.1111/ene.16567