{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["39(4)"],"submitter":["Jamshidi M"],"pubmed_abstract":["<h4>Background</h4>Opioids are prescribed for postsurgical pain management, but a balance between achieving adequate pain control and minimising opioid-related harm is required. This study aimed to investigate the effectiveness of different opioid regimens, in daily dose or treatment duration, prescribed at surgical discharge.<h4>Methods</h4>A systematic search of MEDLINE, EMBASE, CENTRAL, and ICTRP was performed from inception to 12 January 2025. Randomised controlled trials (RCTs) and non-RCTs comparing different daily doses or treatment durations of opioid analgesics were included. All surgeries were included, except those related to cancer treatment or palliative care. Eligible populations were adults (≥ 18 years) or individuals classified as adults according to the criteria of the res"],"journal":["CNS drugs"],"pagination":["345-360"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11909025"],"repository":["biostudies-literature"],"pubmed_title":["Comparative Effectiveness of Different Opioid Regimens, in Daily Dose or Treatment Duration, Prescribed at Surgical Discharge: a Systematic Review and Meta-Analysis."],"pmcid":["PMC11909025"],"pubmed_authors":["Wale J","Horsley M","Jamshidi M","Lin CC","Jones CMP","Jenkin DE","Patanwala AE","Harris IA","Liu C","Langford AV","Adie S"],"additional_accession":[]},"is_claimable":false,"name":"Comparative Effectiveness of Different Opioid Regimens, in Daily Dose or Treatment Duration, Prescribed at Surgical Discharge: a Systematic Review and Meta-Analysis.","description":"<h4>Background</h4>Opioids are prescribed for postsurgical pain management, but a balance between achieving adequate pain control and minimising opioid-related harm is required. This study aimed to investigate the effectiveness of different opioid regimens, in daily dose or treatment duration, prescribed at surgical discharge.<h4>Methods</h4>A systematic search of MEDLINE, EMBASE, CENTRAL, and ICTRP was performed from inception to 12 January 2025. Randomised controlled trials (RCTs) and non-RCTs comparing different daily doses or treatment durations of opioid analgesics were included. All surgeries were included, except those related to cancer treatment or palliative care. Eligible populations were adults (≥ 18 years) or individuals classified as adults according to the criteria of the res","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-04-26T03:23:32.006Z","creation":"2025-04-06T10:51:15.443Z"},"accession":"S-EPMC11909025","cross_references":{"pubmed":["40057907"],"doi":["10.1007/s40263-025-01165-9"]}}