{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10"],"submitter":["Theuriet J"],"pubmed_abstract":["<h4>Objective</h4>This study aimed to compare the frequency of blink reflex's contralateral R1 responses (R1') between patients with amyotrophic lateral sclerosis (ALS), non-ALS motor deficit patients, and healthy volunteers.<h4>Methods</h4>A total of 120 participants were prospectively recruited: 40 with ALS, 40 with a non-ALS motor deficit, and 40 healthy volunteers. Blink reflexes were recorded from orbicularis oculi muscles following supraorbital nerve stimulation.<h4>Results</h4>R1' was more frequent in the ALS group (42.5 %) compared to healthy volunteers (12.5 %, p = 0.00588), and compared to non-ALS patients (7.5 %, p = 0.000789). Bilateral R1' was observed only in ALS patients (22.5 %). No clinically significant difference was found in the latencies or amplitudes of the R1, R2, or"],"journal":["Clinical neurophysiology practice"],"pagination":["47-51"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11909417"],"repository":["biostudies-literature"],"pubmed_title":["Contralateral R1 response in blink reflex in patients with amyotrophic lateral sclerosis."],"pmcid":["PMC11909417"],"pubmed_authors":["Theuriet J","Meens L","Demia M","Pegat A","Svahn J","Vallet AE","Alves L","Roux L","Moussy M","Barsan IC","Dion M","Jomir L","Cluse F","Bohic A","Bonjour M","Bouhour F","Bernard E","Pereon Y"],"additional_accession":[]},"is_claimable":false,"name":"Contralateral R1 response in blink reflex in patients with amyotrophic lateral sclerosis.","description":"<h4>Objective</h4>This study aimed to compare the frequency of blink reflex's contralateral R1 responses (R1') between patients with amyotrophic lateral sclerosis (ALS), non-ALS motor deficit patients, and healthy volunteers.<h4>Methods</h4>A total of 120 participants were prospectively recruited: 40 with ALS, 40 with a non-ALS motor deficit, and 40 healthy volunteers. Blink reflexes were recorded from orbicularis oculi muscles following supraorbital nerve stimulation.<h4>Results</h4>R1' was more frequent in the ALS group (42.5 %) compared to healthy volunteers (12.5 %, p = 0.00588), and compared to non-ALS patients (7.5 %, p = 0.000789). Bilateral R1' was observed only in ALS patients (22.5 %). No clinically significant difference was found in the latencies or amplitudes of the R1, R2, or","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-05-26T14:00:20.608Z","creation":"2025-04-06T11:37:46.12Z"},"accession":"S-EPMC11909417","cross_references":{"pubmed":["40092496"],"doi":["10.1016/j.cnp.2025.02.005"]}}