biostudies-literatureUnknown13Park JK<h4>Background</h4>Conversational agents (CAs; chatbots) are systems with the ability to interact with users using natural human dialogue. They are increasingly used to support interactive knowledge discovery of sensitive topics such as mental health topics. While much of the research on CAs for mental health has focused on adult populations, the insights from such research may not apply to CAs for youth.<h4>Objective</h4>This study aimed to comprehensively evaluate the state-of-the-art research on mental health CAs for youth.<h4>Methods</h4>Following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, we identified 39 peer-reviewed studies specific to mental health CAs designed for youth across 4 databases, including ProQuest, Scopus, Web of Science, anJMIR medical informaticse62758https://www.ebi.ac.uk/biostudies/studies/S-EPMC11909484biostudies-literatureCurrent Landscape and Future Directions for Mental Health Conversational Agents for Youth: Scoping Review.PMC11909484Park JKWisniewski PSingh VKfalseCurrent Landscape and Future Directions for Mental Health Conversational Agents for Youth: Scoping Review.<h4>Background</h4>Conversational agents (CAs; chatbots) are systems with the ability to interact with users using natural human dialogue. They are increasingly used to support interactive knowledge discovery of sensitive topics such as mental health topics. While much of the research on CAs for mental health has focused on adult populations, the insights from such research may not apply to CAs for youth.<h4>Objective</h4>This study aimed to comprehensively evaluate the state-of-the-art research on mental health CAs for youth.<h4>Methods</h4>Following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, we identified 39 peer-reviewed studies specific to mental health CAs designed for youth across 4 databases, including ProQuest, Scopus, Web of Science, an2025-01-01T00:00:00Z2025 Feb2025-04-26T05:47:41.367Z2025-04-06T11:38:06.41ZS-EPMC119094844005373510.2196/62758