{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["22"],"submitter":["Moradicheghamahi J"],"pubmed_abstract":["<h4>Background</h4>Basic science research in cardiopulmonary resuscitation (CPR) is limited by challenges in obtaining haemodynamic data from models that simulate physiological processes. In this study, we assessed the morphology of the heart and lungs and calculated the ejection fractions of cardiac chambers during CPR using a virtual simulation.<h4>Methods</h4>A finite element model of a complete thorax, including internal organs, thoracic rib cage, spine, musculature, and a generic material representing soft tissues, was constructed from magentic resonance images of a man. Twelve chest compression simulations were performed with forces ranging from <i>F</i> = 50 to 600 N. During compression, lung and heart volumes were assessed, and the ejection fraction of each cardiac chamber was calc"],"journal":["Resuscitation plus"],"pagination":["100910"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11914767"],"repository":["biostudies-literature"],"pubmed_title":["Assessment of heart and lung morphology in a single case during cardiopulmonary resuscitation: A virtual simulation."],"pmcid":["PMC11914767"],"pubmed_authors":["Lopez JM","Azeli Y","Herrero J","Moradicheghamahi J","Fortuny G","Puigjaner D"],"additional_accession":[]},"is_claimable":false,"name":"Assessment of heart and lung morphology in a single case during cardiopulmonary resuscitation: A virtual simulation.","description":"<h4>Background</h4>Basic science research in cardiopulmonary resuscitation (CPR) is limited by challenges in obtaining haemodynamic data from models that simulate physiological processes. In this study, we assessed the morphology of the heart and lungs and calculated the ejection fractions of cardiac chambers during CPR using a virtual simulation.<h4>Methods</h4>A finite element model of a complete thorax, including internal organs, thoracic rib cage, spine, musculature, and a generic material representing soft tissues, was constructed from magentic resonance images of a man. Twelve chest compression simulations were performed with forces ranging from <i>F</i> = 50 to 600 N. During compression, lung and heart volumes were assessed, and the ejection fraction of each cardiac chamber was calc","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-04-04T00:06:40.499Z","creation":"2025-04-04T00:06:40.499Z"},"accession":"S-EPMC11914767","cross_references":{"pubmed":["40104099"],"doi":["10.1016/j.resplu.2025.100910"]}}