{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Abdelnaim MA"],"pubmed_abstract":["<h4>Introduction</h4>Irritable bowel syndrome (IBS) is a common condition characterized by abdominal pain and altered bowel habits, affecting around 11% of individuals globally. It is linked to dysregulation of the brain-gut axis, with altered activity and connectivity in various brain regions. IBS patients often have psychiatric comorbidities like anxiety, or obsessive-compulsive disorder (OCD). Deep brain stimulation (DBS) is an established treatment option for severe, therapy-refractory OCD. It has been suggested that DBS for OCD could also have a beneficial effect on accompanying IBS-symptoms.<h4>Methods and patients</h4>Nine patients with treatment-refractory OCD who underwent DBS in the bed nucleus striae terminalis (BNST) have been included in this study (4 males, 5 females, mean ag"],"journal":["Frontiers in psychiatry"],"pagination":["1545318"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11919902"],"repository":["biostudies-literature"],"pubmed_title":["Deep brain stimulation for obsessive compulsive disorder leads to symptom changes of comorbid irritable bowel syndrome."],"pmcid":["PMC11919902"],"pubmed_authors":["Abdelnaim MA","Lang-Hambauer V","Reissmann A","Langguth B","Schlaier J","Hebel T"],"additional_accession":[]},"is_claimable":false,"name":"Deep brain stimulation for obsessive compulsive disorder leads to symptom changes of comorbid irritable bowel syndrome.","description":"<h4>Introduction</h4>Irritable bowel syndrome (IBS) is a common condition characterized by abdominal pain and altered bowel habits, affecting around 11% of individuals globally. It is linked to dysregulation of the brain-gut axis, with altered activity and connectivity in various brain regions. IBS patients often have psychiatric comorbidities like anxiety, or obsessive-compulsive disorder (OCD). Deep brain stimulation (DBS) is an established treatment option for severe, therapy-refractory OCD. It has been suggested that DBS for OCD could also have a beneficial effect on accompanying IBS-symptoms.<h4>Methods and patients</h4>Nine patients with treatment-refractory OCD who underwent DBS in the bed nucleus striae terminalis (BNST) have been included in this study (4 males, 5 females, mean ag","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2025-04-04T14:48:18.523Z","creation":"2025-04-04T14:48:18.523Z"},"accession":"S-EPMC11919902","cross_references":{"pubmed":["40109436"],"doi":["10.3389/fpsyt.2025.1545318"]}}