{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kang DO"],"funding":["Korea University Grant","National Research Foundation of Korea (NRF)","National Research Foundation of Korea"],"pagination":["9391"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11920199"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(1)"],"pubmed_abstract":["Drug-coated balloon (DCB) treatment is an emerging strategy for de novo coronary artery disease (CAD), but procedural optimization remains uncertain. This study analyzed 317 patients who underwent DCB-based intervention for de novo CAD and angiographic follow-up: SR (successful, stent-like result: diameter stenosis < 20% at follow-up angiography, n = 84, 93 lesions) and Non-SR (n = 224, 358 lesions) groups. Baseline clinical and lesion characteristics were similar, except that SR lesions had larger diameter. In SR lesions, specialty balloons were more frequently utilized (p = 0.025), and maximal balloon diameter and balloon-to-artery ratio were significantly greater compared to Non-SR lesions (p < 0.001 and p = 0.008). At a median 8-month follow-up, SR lesions exhibited larger minimal lumi"],"journal":["Scientific reports"],"pubmed_title":["Predictors of optimal angiographic lesion outcomes in drug-coated balloon treatment for de novo coronary artery disease."],"pmcid":["PMC11920199"],"funding_grant_id":["NRF-2021R1F1A1061337","RS-2023-00210960","K2225581","K1923481, K2022971, K2111151, and K2211921"],"pubmed_authors":["Lee JS","Song WH","Kim S","Kim B","Kim SH","Her AY","Shin ES","Kim YH","Ahn JC","Kang DO","Lim SY"],"additional_accession":[]},"is_claimable":false,"name":"Predictors of optimal angiographic lesion outcomes in drug-coated balloon treatment for de novo coronary artery disease.","description":"Drug-coated balloon (DCB) treatment is an emerging strategy for de novo coronary artery disease (CAD), but procedural optimization remains uncertain. This study analyzed 317 patients who underwent DCB-based intervention for de novo CAD and angiographic follow-up: SR (successful, stent-like result: diameter stenosis < 20% at follow-up angiography, n = 84, 93 lesions) and Non-SR (n = 224, 358 lesions) groups. Baseline clinical and lesion characteristics were similar, except that SR lesions had larger diameter. In SR lesions, specialty balloons were more frequently utilized (p = 0.025), and maximal balloon diameter and balloon-to-artery ratio were significantly greater compared to Non-SR lesions (p < 0.001 and p = 0.008). At a median 8-month follow-up, SR lesions exhibited larger minimal lumi","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2026-07-15T08:28:12.969Z","creation":"2025-04-03T23:26:25.007Z"},"accession":"S-EPMC11920199","cross_references":{"pubmed":["40102457"],"doi":["10.1038/s41598-025-92052-2"]}}