{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["167(1)"],"submitter":["Battista F"],"funding":["Università degli Studi di Firenze"],"pubmed_abstract":["<h4>Background</h4>For drug-resistant mesial temporal lobe epilepsy (MTLE), surgery is recommended. There is no evidence of a seizure outcome advantage of temporal lobectomy over other strategies despite the high risks of this surgical procedure.<h4>Methods</h4>We describe a Temporal Resection guided by intraoperative stereo-electroencephalography (iSEEG) and the <sup>18</sup>FluoroDeoxyGlucose PET (<sup>18</sup>FDG PET) (iSP-TR) to treat lesional MTLE. We avoided functional cortical areas using navigated Transcranial Magnetic Stimulation (nTMS).<h4>Conclusion</h4>iSP-TR allows for a spare brain parenchyma compared to temporal lobectomy without compromising seizure outcomes."],"journal":["Acta neurochirurgica"],"pagination":["82"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11922984"],"repository":["biostudies-literature"],"pubmed_title":["The intraoperative SEEG and &lt;sup&gt;18&lt;/sup&gt;FDG-PET tailored temporal lobe resection (iSP-TR) for the tissue-spearing surgical treatment of drug-resistant mesial temporal lobe epilepsy: how we do it."],"pmcid":["PMC11922984"],"pubmed_authors":["Battista F","Grippo A","Della Puppa A","Carrai R"],"additional_accession":[]},"is_claimable":false,"name":"The intraoperative SEEG and &lt;sup&gt;18&lt;/sup&gt;FDG-PET tailored temporal lobe resection (iSP-TR) for the tissue-spearing surgical treatment of drug-resistant mesial temporal lobe epilepsy: how we do it.","description":"<h4>Background</h4>For drug-resistant mesial temporal lobe epilepsy (MTLE), surgery is recommended. There is no evidence of a seizure outcome advantage of temporal lobectomy over other strategies despite the high risks of this surgical procedure.<h4>Methods</h4>We describe a Temporal Resection guided by intraoperative stereo-electroencephalography (iSEEG) and the <sup>18</sup>FluoroDeoxyGlucose PET (<sup>18</sup>FDG PET) (iSP-TR) to treat lesional MTLE. We avoided functional cortical areas using navigated Transcranial Magnetic Stimulation (nTMS).<h4>Conclusion</h4>iSP-TR allows for a spare brain parenchyma compared to temporal lobectomy without compromising seizure outcomes.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-04-18T12:50:07.411Z","creation":"2025-04-06T22:12:56.895Z"},"accession":"S-EPMC11922984","cross_references":{"pubmed":["40106065"],"doi":["10.1007/s00701-025-06491-x"]}}