biostudies-literatureUnknown5(3)Agnihotri AP<h4>Purpose</h4>To review and evaluate the current literature on the application and impact of large language models (LLMs) in the field of ophthalmology, focusing on studies published in high-ranking ophthalmology journals.<h4>Design</h4>This is a retrospective review of published articles.<h4>Participants</h4>This study did not involve human participation.<h4>Methods</h4>Articles published in the first quartile (Q1) of ophthalmology journals on Scimago Journal & Country Rank discussing different LLMs up to June 7, 2024, were reviewed, parsed, and analyzed.<h4>Main outcome measures</h4>All available articles were parsed and analyzed, which included the article and author characteristics and data regarding the LLM used and its applications, focusing on its use in medical education, clinicaOphthalmology science100681https://www.ebi.ac.uk/biostudies/studies/S-EPMC11925577biostudies-literatureLarge Language Models in Ophthalmology: A Review of Publications from Top Ophthalmology Journals.PMC11925577Artiaga JCMAgnihotri APKalaw FGPNagel IDSosuan GMNGuevarra MCBfalseLarge Language Models in Ophthalmology: A Review of Publications from Top Ophthalmology Journals.<h4>Purpose</h4>To review and evaluate the current literature on the application and impact of large language models (LLMs) in the field of ophthalmology, focusing on studies published in high-ranking ophthalmology journals.<h4>Design</h4>This is a retrospective review of published articles.<h4>Participants</h4>This study did not involve human participation.<h4>Methods</h4>Articles published in the first quartile (Q1) of ophthalmology journals on Scimago Journal & Country Rank discussing different LLMs up to June 7, 2024, were reviewed, parsed, and analyzed.<h4>Main outcome measures</h4>All available articles were parsed and analyzed, which included the article and author characteristics and data regarding the LLM used and its applications, focusing on its use in medical education, clinica2025-01-01T00:00:00Z2025 May-Jun2025-04-03T23:24:04.976Z2025-04-03T23:24:04.976ZS-EPMC119255774011471210.1016/j.xops.2024.100681