{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["23(1)"],"submitter":["Xie X"],"pubmed_abstract":["<h4>Background</h4>Rapid urbanization is underway in China. However, the impact of urbanization on frailty remains unclear. This study aims to investigate the relationship between urbanization and frailty among middle-aged and older adults.<h4>Methods</h4>We analyzed nationally representative data from the China Health and Retirement Longitudinal Study (CHARLS) spanning 2011 to 2018. After applying inclusion and exclusion criteria, 10,758 non-frail individuals at baseline were analyzed. The exposure of interest was the comprehensive urbanization level. Urbanization level (0.072-0.689) was assessed using the entropy method. Frailty was assessed using the frailty index (FI), which ranges from 0 to 100. Frailty was defined as FI ≥ 25, and the urbanization-frailty association was assessed usin"],"journal":["BMC medicine"],"pagination":["171"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11934686"],"repository":["biostudies-literature"],"pubmed_title":["Association between urbanization levels and frailty among middle-aged and older adults in China: evidence from the CHARLS."],"pmcid":["PMC11934686"],"pubmed_authors":["Sun L","Xie X","Que J","Sun T","Yang F"],"additional_accession":[]},"is_claimable":false,"name":"Association between urbanization levels and frailty among middle-aged and older adults in China: evidence from the CHARLS.","description":"<h4>Background</h4>Rapid urbanization is underway in China. However, the impact of urbanization on frailty remains unclear. This study aims to investigate the relationship between urbanization and frailty among middle-aged and older adults.<h4>Methods</h4>We analyzed nationally representative data from the China Health and Retirement Longitudinal Study (CHARLS) spanning 2011 to 2018. After applying inclusion and exclusion criteria, 10,758 non-frail individuals at baseline were analyzed. The exposure of interest was the comprehensive urbanization level. Urbanization level (0.072-0.689) was assessed using the entropy method. Frailty was assessed using the frailty index (FI), which ranges from 0 to 100. Frailty was defined as FI ≥ 25, and the urbanization-frailty association was assessed usin","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-06-25T03:04:37.1Z","creation":"2025-06-25T03:04:37.1Z"},"accession":"S-EPMC11934686","cross_references":{"pubmed":["40128743"],"doi":["10.1186/s12916-025-03961-y"]}}