{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(3)"],"submitter":["Rodeghiero F"],"funding":["European Hematology Association"],"pubmed_abstract":["In a previous paper, a comprehensive clinicopathologic approach to mild and moderate bleeding disorders (MBD) was proposed by an international working group (IWG) as a part of a project promoted by the European Hematology Association (EHA) on the development of guidelines on the various MBDs. A single pre-diagnosis grade 4 bleeding event according to the ISTH-BAT scale or a comparable event after diagnosis was considered sufficient to classify a patient as affected by a severe bleeding disorder (SBD). In this article, the original IWG integrated by experts and patients' representatives proposed by the European Haemophilia Consortium (EHC) and European Association of Haemophilia and Allied Disorders (EAHAD) applied these criteria to mild and moderate hemophilia A and B to establish the prop"],"journal":["HemaSphere"],"pagination":["e70111"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11934897"],"repository":["biostudies-literature"],"pubmed_title":["Mild or moderate hemophilia is not always a mild or moderate bleeding disorder: Back to the clinical phenotype."],"pmcid":["PMC11934897"],"pubmed_authors":["Key NS","Bodo I","Castaman G","Noris P","Zieger B","Srivastava A","Mezzano D","Casini A","Pontalto L","Abdul-Kadir R","Lillicrap D","Berntorp E","Windyga J","Gresele P","Degenaar-Dujardin M","Ragni MV","Rodeghiero F","Fijnvandraat K","Ghiotto L","Pabinger I","Tosetto A","Makris M","Leebeek FWG","Meijer S","Lassila R","Silva D"],"additional_accession":[]},"is_claimable":false,"name":"Mild or moderate hemophilia is not always a mild or moderate bleeding disorder: Back to the clinical phenotype.","description":"In a previous paper, a comprehensive clinicopathologic approach to mild and moderate bleeding disorders (MBD) was proposed by an international working group (IWG) as a part of a project promoted by the European Hematology Association (EHA) on the development of guidelines on the various MBDs. A single pre-diagnosis grade 4 bleeding event according to the ISTH-BAT scale or a comparable event after diagnosis was considered sufficient to classify a patient as affected by a severe bleeding disorder (SBD). In this article, the original IWG integrated by experts and patients' representatives proposed by the European Haemophilia Consortium (EHC) and European Association of Haemophilia and Allied Disorders (EAHAD) applied these criteria to mild and moderate hemophilia A and B to establish the prop","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-07-02T03:04:29.088Z","creation":"2025-07-02T03:04:29.088Z"},"accession":"S-EPMC11934897","cross_references":{"pubmed":["40134524"],"doi":["10.1002/hem3.70111"]}}