{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["60(3)"],"submitter":["Zhang Y"],"pubmed_abstract":["<h4>Context</h4>Pain-related movement fear is a contributing factor to residual pain and functional deficits in chronic ankle instability (CAI), but its underlying neural mechanisms remain unclear.<h4>Objective</h4>We aimed to (1) delineate whether participants with CAI exhibit discernible differences in specific emotion- and pain-related brain regions compared with a healthy control (HC) cohort and (2) explore potential neural mechanisms underlying pain and fear in participants with CAI, with an emphasis on investigating possible associations with pain-related neural plasticity.<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>University research laboratory.<h4>Patients or other participants</h4>Twenty-eight participants with CAI (17 men and 11 women; age = 31.28 ± 6.31 years) and 28 H"],"journal":["Journal of athletic training"],"pagination":["210-217"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11935306"],"repository":["biostudies-literature"],"pubmed_title":["Association Between Neural Plasticity and Pain-Related Fear in Chronic Ankle Instability: A Structural Neuroimaging Study."],"pmcid":["PMC11935306"],"pubmed_authors":["Hua Y","Yu L","Tao W","Pan S","Zhang Y","Guo G","Wang H","Xue X","Cao R"],"additional_accession":[]},"is_claimable":false,"name":"Association Between Neural Plasticity and Pain-Related Fear in Chronic Ankle Instability: A Structural Neuroimaging Study.","description":"<h4>Context</h4>Pain-related movement fear is a contributing factor to residual pain and functional deficits in chronic ankle instability (CAI), but its underlying neural mechanisms remain unclear.<h4>Objective</h4>We aimed to (1) delineate whether participants with CAI exhibit discernible differences in specific emotion- and pain-related brain regions compared with a healthy control (HC) cohort and (2) explore potential neural mechanisms underlying pain and fear in participants with CAI, with an emphasis on investigating possible associations with pain-related neural plasticity.<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>University research laboratory.<h4>Patients or other participants</h4>Twenty-eight participants with CAI (17 men and 11 women; age = 31.28 ± 6.31 years) and 28 H","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2026-07-16T23:33:17.112Z","creation":"2026-07-12T03:11:23.92Z"},"accession":"S-EPMC11935306","cross_references":{"pubmed":["39287087"],"doi":["10.4085/1062-6050-0214.24"]}}