{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(21)"],"submitter":["Mokhtari A"],"pubmed_abstract":["<h4>Background</h4>European guidelines recommend the use of a 0h/1h hs-cTn (high-sensitivity cardiac troponin) protocol in patients with acute chest pain. We aimed to determine the performance of this protocol in routine care when supplemented with patient history and ECG and a recommendation to refrain from noninvasive testing in low-risk patients.<h4>Methods and results</h4>This was a pre- and postimplementation study with concurrent controls. Patients with chest pain were enrolled at 5 Swedish emergency departments (EDs) during a 10-month period in both 2017 and 2018. All hospitals used a 0h/3h hs-cTnT protocol in 2017 and 3 EDs implemented a 0h/1h hs-cTnT protocol during 10 months in 2018. The 2 coprimary outcomes were the incidence of acute myocardial infarction and all-cause death wi"],"journal":["Journal of the American Heart Association"],"pagination":["e036307"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11935679"],"repository":["biostudies-literature"],"pubmed_title":["Effectiveness and Safety of the ESC-TROP (European Society of Cardiology 0h/1h Troponin Rule-Out Protocol) Trial."],"pmcid":["PMC11935679"],"pubmed_authors":["Ellehuus C","Lindahl B","Mokhtari A","Bjork J","Sandgren J","Ekstrom U","Ekelund U","Hard Af Segerstad C","Khoshnood A","Forberg JL"],"additional_accession":[]},"is_claimable":false,"name":"Effectiveness and Safety of the ESC-TROP (European Society of Cardiology 0h/1h Troponin Rule-Out Protocol) Trial.","description":"<h4>Background</h4>European guidelines recommend the use of a 0h/1h hs-cTn (high-sensitivity cardiac troponin) protocol in patients with acute chest pain. We aimed to determine the performance of this protocol in routine care when supplemented with patient history and ECG and a recommendation to refrain from noninvasive testing in low-risk patients.<h4>Methods and results</h4>This was a pre- and postimplementation study with concurrent controls. Patients with chest pain were enrolled at 5 Swedish emergency departments (EDs) during a 10-month period in both 2017 and 2018. All hospitals used a 0h/3h hs-cTnT protocol in 2017 and 3 EDs implemented a 0h/1h hs-cTnT protocol during 10 months in 2018. The 2 coprimary outcomes were the incidence of acute myocardial infarction and all-cause death wi","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-06-01T19:10:10.986Z","creation":"2025-07-10T03:08:26.815Z"},"accession":"S-EPMC11935679","cross_references":{"pubmed":["39470043"],"doi":["10.1161/JAHA.124.036307"]}}