{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Shen S"],"funding":["National Key P & D Program of China"],"pagination":["929"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11945280"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(6)"],"pubmed_abstract":["Amino acid metabolism constitutes a major metabolic pathway in plants, playing an important role in the modulation of plant responses to stress. In this study, we investigated the amino acid metabolism responses of <i>M. sativa</i> (<i>Medicago sativa</i> L.) and <i>M. truncatula</i> (<i>Medicago truncatula</i> L.) plants under salt stress using transcriptomic and proteomic approaches to elucidate their salt stress tolerance mechanisms in relation to the regulation of amino acid homeostasis. Transcriptome and proteome sequencing followed by Kyoto Gene and Genome Encyclopedia enrichment analysis revealed 34 differentially expressed genes and 45 differentially expressed proteins involved in valine, leucine, and isoleucine degradation, tyrosine metabolism, and glutathione metabolism. Signific"],"journal":["Plants (Basel, Switzerland)"],"pubmed_title":["The Involvement of Amino Acid Metabolism in the Mechanisms of Salt Tolerance Adaptation in &lt;i&gt;Medicago sativa&lt;/i&gt; and &lt;i&gt;Medicago truncatula&lt;/i&gt;."],"pmcid":["PMC11945280"],"funding_grant_id":["NO. 2022YFE0113400"],"pubmed_authors":["Liu H","Li J","Kang B","Lu Y","Ahmad I","Gao Y","Shen S","Wang X","Pan L","Bai Y","Wang J","Yin J"],"additional_accession":[]},"is_claimable":false,"name":"The Involvement of Amino Acid Metabolism in the Mechanisms of Salt Tolerance Adaptation in &lt;i&gt;Medicago sativa&lt;/i&gt; and &lt;i&gt;Medicago truncatula&lt;/i&gt;.","description":"Amino acid metabolism constitutes a major metabolic pathway in plants, playing an important role in the modulation of plant responses to stress. In this study, we investigated the amino acid metabolism responses of <i>M. sativa</i> (<i>Medicago sativa</i> L.) and <i>M. truncatula</i> (<i>Medicago truncatula</i> L.) plants under salt stress using transcriptomic and proteomic approaches to elucidate their salt stress tolerance mechanisms in relation to the regulation of amino acid homeostasis. Transcriptome and proteome sequencing followed by Kyoto Gene and Genome Encyclopedia enrichment analysis revealed 34 differentially expressed genes and 45 differentially expressed proteins involved in valine, leucine, and isoleucine degradation, tyrosine metabolism, and glutathione metabolism. Signific","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2026-04-18T03:15:59.527Z","creation":"2026-04-18T03:11:04.102Z"},"accession":"S-EPMC11945280","cross_references":{"pubmed":["40265823"],"doi":["10.3390/plants14060929"]}}