biostudies-literatureUnknown9Zhu J<h4>Background</h4>The worldwide introduction of ChatGPT in November 2022 may have changed how its users perceive and interact with other chatbots. This possibility may confound the comparison of responses to pre-ChatGPT and post-ChatGPT iterations of pre-existing chatbots, in turn affecting the direction of their evolution. Before the release of ChatGPT, we created a therapeutic chatbot, MIBot, whose goal is to use motivational interviewing to guide smokers toward making the decision to quit smoking. We were concerned that measurements going forward would not be comparable to those in the past, impacting the evaluation of future changes to the chatbot.<h4>Objective</h4>The aim of the study is to explore changes in how users interact with MIBot after the release of ChatGPT and examine the JMIR formative researche56973https://www.ebi.ac.uk/biostudies/studies/S-EPMC11952273biostudies-literatureThe Impact of ChatGPT Exposure on User Interactions With a Motivational Interviewing Chatbot: Quasi-Experimental Study.PMC11952273Brown AZhu JWang CRose JVeldhuizen SAbdelwahab MDong ASelby PfalseThe Impact of ChatGPT Exposure on User Interactions With a Motivational Interviewing Chatbot: Quasi-Experimental Study.<h4>Background</h4>The worldwide introduction of ChatGPT in November 2022 may have changed how its users perceive and interact with other chatbots. This possibility may confound the comparison of responses to pre-ChatGPT and post-ChatGPT iterations of pre-existing chatbots, in turn affecting the direction of their evolution. Before the release of ChatGPT, we created a therapeutic chatbot, MIBot, whose goal is to use motivational interviewing to guide smokers toward making the decision to quit smoking. We were concerned that measurements going forward would not be comparable to those in the past, impacting the evaluation of future changes to the chatbot.<h4>Objective</h4>The aim of the study is to explore changes in how users interact with MIBot after the release of ChatGPT and examine the 2025-01-01T00:00:00Z2025 Mar2026-03-13T10:32:50.265Z2025-08-13T03:04:28.952ZS-EPMC119522734011749610.2196/56973