{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang H"],"funding":["EC | European Regional Development Fund (Europski Fond za Regionalni Razvoj)","Norges Forskningsråd (Research Council of Norway)"],"pagination":["510"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11953307"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8(1)"],"pubmed_abstract":["Giant viruses are extraordinary members of the virosphere due to their structural complexity and high diversity in gene content. Haptophytes are ecologically important primary producers in the ocean, and all known viruses that infect haptophytes are giant viruses. However, little is known about the specifics of their infection cycles and the responses they trigger in their host cells. Our in-depth electron microscopic, phylogenomic and virion proteomic analyses of two haptophyte-infecting giant viruses, Haptolina ericina virus RF02 (HeV RF02) and Prymnesium kappa virus RF02 (PkV RF02), unravel their large capacity for host manipulation and arsenals that function during the infection cycle from virus entry to release. The virus infection induces significant morphological changes in the host"],"journal":["Communications biology"],"pubmed_title":["Haptophyte-infecting viruses change the genome condensing proteins of dinoflagellates."],"pmcid":["PMC11953307"],"funding_grant_id":["PID2022-136456NB-I00/AEI/10.13039/501100011033","294363"],"pubmed_authors":["Blanc-Mathieu R","Ogata H","Otaegi-Ugartemendia S","Langvad MR","Brandt D","Wang H","San Martin C","Kalinowski J","Dahle H","Condezo GN","Meng L","Sandaa RA","Stokke R"],"additional_accession":[]},"is_claimable":false,"name":"Haptophyte-infecting viruses change the genome condensing proteins of dinoflagellates.","description":"Giant viruses are extraordinary members of the virosphere due to their structural complexity and high diversity in gene content. Haptophytes are ecologically important primary producers in the ocean, and all known viruses that infect haptophytes are giant viruses. However, little is known about the specifics of their infection cycles and the responses they trigger in their host cells. Our in-depth electron microscopic, phylogenomic and virion proteomic analyses of two haptophyte-infecting giant viruses, Haptolina ericina virus RF02 (HeV RF02) and Prymnesium kappa virus RF02 (PkV RF02), unravel their large capacity for host manipulation and arsenals that function during the infection cycle from virus entry to release. The virus infection induces significant morphological changes in the host","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2026-06-01T06:07:46.393Z","creation":"2026-04-08T09:52:52.04Z"},"accession":"S-EPMC11953307","cross_references":{"pubmed":["40155463"],"doi":["10.1038/s42003-025-07905-3"]}}