{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gomes FL"],"funding":["TKI Green Chemistry and Circularity","Dutch Research Council (NWO)","Health~Holland"],"pagination":["18179-18193"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11955951"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(12)"],"pubmed_abstract":["Particles are essential building blocks in nanomedicine and cell engineering. Their administration often involves blood contact, which demands a hemocompatible material profile. Coating particles with isolated cell membranes is a common strategy to improve hemocompatibility, but this solution is nonscalable and potentially immunogenic. Cell membrane-like lipid coatings are a promising alternative, as lipids can be synthesized on a large scale and used to create safe cell membrane-like supported bilayers. However, a method to controllably and scalably lipid-coat a wide range of particles has remained elusive. Here, an on-particle solvent-assisted lipid coating (OPSALC) method is introduced as an innovative technique to endow various types of particles with cell membrane-like coatings. Coati"],"journal":["ACS applied materials & interfaces"],"pubmed_title":["OPSALC: On-Particle Solvent-Assisted Lipid Coating to Create Erythrocyte Membrane-like Coatings with Improved Hemocompatibility."],"pmcid":["PMC11955951"],"funding_grant_id":["CHEMIE.PGT.2023.017","OCENW.XS23.4.046","LSHM19074"],"pubmed_authors":["van Weerd J","Leijten J","Gomes FL","Edelbroek R","Jonkheijm P","Wasserberg D"],"additional_accession":[]},"is_claimable":false,"name":"OPSALC: On-Particle Solvent-Assisted Lipid Coating to Create Erythrocyte Membrane-like Coatings with Improved Hemocompatibility.","description":"Particles are essential building blocks in nanomedicine and cell engineering. Their administration often involves blood contact, which demands a hemocompatible material profile. Coating particles with isolated cell membranes is a common strategy to improve hemocompatibility, but this solution is nonscalable and potentially immunogenic. Cell membrane-like lipid coatings are a promising alternative, as lipids can be synthesized on a large scale and used to create safe cell membrane-like supported bilayers. However, a method to controllably and scalably lipid-coat a wide range of particles has remained elusive. Here, an on-particle solvent-assisted lipid coating (OPSALC) method is introduced as an innovative technique to endow various types of particles with cell membrane-like coatings. Coati","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-07-02T03:04:56.442Z","creation":"2025-07-02T03:04:56.442Z"},"accession":"S-EPMC11955951","cross_references":{"pubmed":["40079786"],"doi":["10.1021/acsami.5c02103"]}}