{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["77(2)"],"submitter":["Emile SH"],"pubmed_abstract":["Pelvic exenteration (PE) entails an en bloc resection of locally advanced primary or recurrent rectal cancer. This study aimed to assess the short-term and survival outcomes of minimally invasive (MI)- and open PE. A retrospective cohort analysis of patients with stage III rectal adenocarcinoma treated with PE from the National Cancer Database (2010-2019) was conducted. Open and MI-PE were matched for baseline and treatment characteristics using 2:1 propensity score matching. Primary outcomes were 30- and 90-day mortality; secondary outcomes included 30-day readmission, hospital stay, surgical margins, lymph node yield, and overall survival (OS). PE was performed in 1010 (1.9%) of 52,242 patients; 705 (69.8%) were open and 304 were (30.2%) MI procedures. After matching, 169 patients in the"],"journal":["Updates in surgery"],"pagination":["267-276"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11961522"],"repository":["biostudies-literature"],"pubmed_title":["Propensity-score matched outcomes of minimally invasive and open pelvic exenteration in locally advanced rectal cancer."],"pmcid":["PMC11961522"],"pubmed_authors":["Gefen R","Horesh N","Dourado J","Wexner SD","Emile SH","Garoufalia Z","Salama E"],"additional_accession":[]},"is_claimable":false,"name":"Propensity-score matched outcomes of minimally invasive and open pelvic exenteration in locally advanced rectal cancer.","description":"Pelvic exenteration (PE) entails an en bloc resection of locally advanced primary or recurrent rectal cancer. This study aimed to assess the short-term and survival outcomes of minimally invasive (MI)- and open PE. A retrospective cohort analysis of patients with stage III rectal adenocarcinoma treated with PE from the National Cancer Database (2010-2019) was conducted. Open and MI-PE were matched for baseline and treatment characteristics using 2:1 propensity score matching. Primary outcomes were 30- and 90-day mortality; secondary outcomes included 30-day readmission, hospital stay, surgical margins, lymph node yield, and overall survival (OS). PE was performed in 1010 (1.9%) of 52,242 patients; 705 (69.8%) were open and 304 were (30.2%) MI procedures. After matching, 169 patients in the","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-06-28T03:05:09.328Z","creation":"2025-06-28T03:05:09.328Z"},"accession":"S-EPMC11961522","cross_references":{"pubmed":["39821600"],"doi":["10.1007/s13304-025-02102-7"]}}