biostudies-literatureUnknown15(1)Wang YLung cancer is a leading cause of cancer-related morbidity and mortality worldwide. Diabetes, as a common metabolic disorder, further increases the risk of cardiovascular damage. Studies have shown that myocardial cells in diabetic patients are more vulnerable to the toxic effects of cancer treatments, thereby raising the risk of heart failure. Therefore, cardiovascular risk assessment in lung cancer patients with diabetes is particularly important. The Inflammatory Burden Index (IBI) is a biomarker that reflects systemic inflammation, combining the levels of C-reactive protein (CRP), neutrophils, and lymphocytes. It has been shown to be a significant prognostic indicator in various cancer populations. This study aims to investigate the predictive ability of IBI and the triglyceride-glucosScientific reports11291https://www.ebi.ac.uk/biostudies/studies/S-EPMC11965416biostudies-literatureThe inflammation burden index can predict the cardiac injury following antitumour therapy in lung cancer patients with diabetes.PMC11965416Liu YLiu JLi CPan DHuan CZhang XWang GPu HWang YWu WfalseThe inflammation burden index can predict the cardiac injury following antitumour therapy in lung cancer patients with diabetes.Lung cancer is a leading cause of cancer-related morbidity and mortality worldwide. Diabetes, as a common metabolic disorder, further increases the risk of cardiovascular damage. Studies have shown that myocardial cells in diabetic patients are more vulnerable to the toxic effects of cancer treatments, thereby raising the risk of heart failure. Therefore, cardiovascular risk assessment in lung cancer patients with diabetes is particularly important. The Inflammatory Burden Index (IBI) is a biomarker that reflects systemic inflammation, combining the levels of C-reactive protein (CRP), neutrophils, and lymphocytes. It has been shown to be a significant prognostic indicator in various cancer populations. This study aims to investigate the predictive ability of IBI and the triglyceride-glucos2025-01-01T00:00:00Z2025 Apr2025-07-07T03:08:37.534Z2025-07-07T03:08:37.534ZS-EPMC119654164017550910.1038/s41598-025-95758-5