{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Figueiredo da Silva J"],"funding":["H2020 Marie Sklodowska-Curie Actions","Swiss National Science Foundation","University of Bern"],"pagination":["8071-8080"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11966745"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["41(12)"],"pubmed_abstract":["Numerous metabolic processes in nature are governed by extrinsic stimuli such as light and pH variations, which afford opportunities for synthetic and biological applications. In developing a multisensor apparatus, we have integrated submicrometer purple membrane patches, each harboring bacteriorhodopsin, onto a surface. Bacteriorhodopsin is a light-driven proton pump. We conducted monitoring of the interactions between this system and a pH-responsive supramolecular hydrogel to evaluate fibrous matrix growth. Initial photostimulation induced localized reductions in pH at the membrane surface, thereby catalyzing fibrogenesis within the hydrogel. Utilizing liquid atomic force microscopy alongside confocal laser scanning microscopy, we observed the hydrogel's morphogenesis and structural adap"],"journal":["Langmuir : the ACS journal of surfaces and colloids"],"pubmed_title":["Control of a Gel-Forming Chemical Reaction Network Using Light-Triggered Proton Pumps."],"pmcid":["PMC11966745"],"funding_grant_id":["00021 179148","812868"],"pubmed_authors":["Figueiredo da Silva J","Bus M","van Esch JH","Knoll AW","Roshanasan A","Wolf H","Fotiadis D"],"additional_accession":[]},"is_claimable":false,"name":"Control of a Gel-Forming Chemical Reaction Network Using Light-Triggered Proton Pumps.","description":"Numerous metabolic processes in nature are governed by extrinsic stimuli such as light and pH variations, which afford opportunities for synthetic and biological applications. In developing a multisensor apparatus, we have integrated submicrometer purple membrane patches, each harboring bacteriorhodopsin, onto a surface. Bacteriorhodopsin is a light-driven proton pump. We conducted monitoring of the interactions between this system and a pH-responsive supramolecular hydrogel to evaluate fibrous matrix growth. Initial photostimulation induced localized reductions in pH at the membrane surface, thereby catalyzing fibrogenesis within the hydrogel. Utilizing liquid atomic force microscopy alongside confocal laser scanning microscopy, we observed the hydrogel's morphogenesis and structural adap","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-07-07T03:08:27.002Z","creation":"2025-07-07T03:08:27.002Z"},"accession":"S-EPMC11966745","cross_references":{"pubmed":["40105355"],"doi":["10.1021/acs.langmuir.4c04581"]}}