{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["20(4)"],"submitter":["Sanchez-Pujol J"],"pubmed_abstract":["<h4>Objective</h4>Some reports suggest monosodium urate (MSU) crystals may deposit in artery walls. This exploratory study evaluated the capacity of optical coherence tomography (OCT) to detect MSU crystals in vessel phantoms.<h4>Methods</h4>We used 3D-printed blood vessel phantoms made of photosensitive acrylic resins, with varying compliances. 0.1cc volume injections of centrifugated human synovial fluids containing MSU crystals, calcium pyrophosphate crystals or 0.9% saline were performed in four predefined locations in the phantoms. OCT was subsequently performed in a blinded manner by two cardiologists, experts in the technique. Two exploratory definitions for MSU crystal deposits were used, depicting a lesion with high attenuation (#1) or also with a linear morphology (#2). Diagnosti"],"journal":["PloS one"],"pagination":["e0320742"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11967950"],"repository":["biostudies-literature"],"pubmed_title":["Could optical coherence tomography detect monosodium urate crystal deposition at artery walls? An exploratory, phantom-based study."],"pmcid":["PMC11967950"],"pubmed_authors":["Andres M","Ruiz-Nodar JM","Sanchez-Pujol J","Valencia J"],"additional_accession":[]},"is_claimable":false,"name":"Could optical coherence tomography detect monosodium urate crystal deposition at artery walls? An exploratory, phantom-based study.","description":"<h4>Objective</h4>Some reports suggest monosodium urate (MSU) crystals may deposit in artery walls. This exploratory study evaluated the capacity of optical coherence tomography (OCT) to detect MSU crystals in vessel phantoms.<h4>Methods</h4>We used 3D-printed blood vessel phantoms made of photosensitive acrylic resins, with varying compliances. 0.1cc volume injections of centrifugated human synovial fluids containing MSU crystals, calcium pyrophosphate crystals or 0.9% saline were performed in four predefined locations in the phantoms. OCT was subsequently performed in a blinded manner by two cardiologists, experts in the technique. Two exploratory definitions for MSU crystal deposits were used, depicting a lesion with high attenuation (#1) or also with a linear morphology (#2). Diagnosti","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-05-29T16:49:37.592Z","creation":"2025-07-11T03:03:57.783Z"},"accession":"S-EPMC11967950","cross_references":{"pubmed":["40179104"],"doi":["10.1371/journal.pone.0320742"]}}