{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chen Y"],"funding":["National Key Research and Development Program of China"],"pagination":["e13802"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11969239"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["58(4)"],"pubmed_abstract":["Cells face two challenges after transplantation: recognition and killing by lymphocytes, and cell apoptosis induced by the transplantation environment. Our hypoimmune cells aim to address these two challenges through editing of immunomodulatory proteins and overexpression of anti-apoptotic proteins."],"journal":["Cell proliferation"],"pubmed_title":["Genetically Engineered Hypoimmune Human Muscle Progenitor Cells Can Reduce Immune Rejection."],"pmcid":["PMC11969239"],"funding_grant_id":["2019YFA0801700"],"pubmed_authors":["Yue C","Liu X","Wang P","Ma S","Liu K","Shyh-Chang N","Chen Y","Zhao T","Cheng Y"],"additional_accession":[]},"is_claimable":false,"name":"Genetically Engineered Hypoimmune Human Muscle Progenitor Cells Can Reduce Immune Rejection.","description":"Cells face two challenges after transplantation: recognition and killing by lymphocytes, and cell apoptosis induced by the transplantation environment. Our hypoimmune cells aim to address these two challenges through editing of immunomodulatory proteins and overexpression of anti-apoptotic proteins.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-07-11T03:04:06.311Z","creation":"2025-07-11T03:04:06.311Z"},"accession":"S-EPMC11969239","cross_references":{"pubmed":["39777760"],"doi":["10.1111/cpr.13802"]}}