biostudies-literatureUnknown29(1)Le Goff M<h4>Background</h4>Liver abscess (LA) is a rare but potentially serious condition with a high mortality rate. Current epidemiological data of LA patients requiring intensive care unit (ICU) admission are limited.<h4>Methods</h4>This multicentre retrospective study included adults admitted to 24 ICUs in France between January 2010 and December 2020. Risk factors for mortality were identified by multivariate analysis. A propensity score was used to adjust for confounders related to the presence of portal vein thrombosis.<h4>Results</h4>335 patients were enrolled. The median age was 66 years [53-73] and 68% were male. Commons comorbidities included diabetes (29.9%) and cancer or haematological disease. Septic shock was the main reason for admission (58%). The median SAPS2 score at ICU admissiCritical care (London, England)146https://www.ebi.ac.uk/biostudies/studies/S-EPMC11974115biostudies-literaturePrognosis of liver abscess in the intensive care unit (POLAIR), a multicentre observational study.PMC11974115Rossi GDas VMartino FLeclerc MMoncomble ECalvet LYvin ELaurent VCadoz CSchmidt Jde Montmollin EToussaint AHerault AIssa NMariotte EMeunier JLemiale VVoriot GGarret CDecavele MArgaud LGarcon PReuter DFraisse MSaccheri CLe Goff MfalsePrognosis of liver abscess in the intensive care unit (POLAIR), a multicentre observational study.<h4>Background</h4>Liver abscess (LA) is a rare but potentially serious condition with a high mortality rate. Current epidemiological data of LA patients requiring intensive care unit (ICU) admission are limited.<h4>Methods</h4>This multicentre retrospective study included adults admitted to 24 ICUs in France between January 2010 and December 2020. Risk factors for mortality were identified by multivariate analysis. A propensity score was used to adjust for confounders related to the presence of portal vein thrombosis.<h4>Results</h4>335 patients were enrolled. The median age was 66 years [53-73] and 68% were male. Commons comorbidities included diabetes (29.9%) and cancer or haematological disease. Septic shock was the main reason for admission (58%). The median SAPS2 score at ICU admissi2025-01-01T00:00:00Z2025 Apr2025-07-12T03:04:17.174Z2025-07-12T03:04:17.174ZS-EPMC119741154019750810.1186/s13054-025-05376-w