{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hartmann D"],"funding":["Biotechnology and Biological Sciences Research Council","Engineering and Physical Sciences Research Council"],"pagination":["e202501122"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11976202"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["64(15)"],"pubmed_abstract":["Helical assemblies of organic dyes are ubiquitous chiral organic materials, with valuable properties including chiroptical switching due to the dynamic nature of supramolecular chirality. Herein, we report a novel chiral bis-perylene diimide macrocycle, which acts as a discrete molecular model for a chiral supramolecular assembly. Point chirality is installed through amino acid-derived imide groups which, upon macrocyclization, is translated into helical chirality in the perylene diimide dimer. In solution, the macrocycle's chiroptical properties are switchable, with both the sign (+/-) and amplitude (on/off) of the signal tuned using solvent and molecular recognition stimuli respectively. The chiral structure-property relationships identified from this macrocycle are important for the des"],"journal":["Angewandte Chemie (International ed. in English)"],"pubmed_title":["A Bis-Perylene Diimide Macrocycle Chiroptical Switch."],"pmcid":["PMC11976202"],"funding_grant_id":["BB/X001172/1","BB/S017615/1","EP/X040259/1","EP/W037661/1"],"pubmed_authors":["Barendt TA","Penty SE","Pal R","Hartmann D","Zwijnenburg MA"],"additional_accession":[]},"is_claimable":false,"name":"A Bis-Perylene Diimide Macrocycle Chiroptical Switch.","description":"Helical assemblies of organic dyes are ubiquitous chiral organic materials, with valuable properties including chiroptical switching due to the dynamic nature of supramolecular chirality. Herein, we report a novel chiral bis-perylene diimide macrocycle, which acts as a discrete molecular model for a chiral supramolecular assembly. Point chirality is installed through amino acid-derived imide groups which, upon macrocyclization, is translated into helical chirality in the perylene diimide dimer. In solution, the macrocycle's chiroptical properties are switchable, with both the sign (+/-) and amplitude (on/off) of the signal tuned using solvent and molecular recognition stimuli respectively. The chiral structure-property relationships identified from this macrocycle are important for the des","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-07-06T03:04:36.454Z","creation":"2025-07-06T03:04:36.454Z"},"accession":"S-EPMC11976202","cross_references":{"pubmed":["39888156"],"doi":["10.1002/anie.202501122"]}}