{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang J"],"funding":["the Natural Science Foundation of Beijing Municipality of China","the National Programs for Brain Science and Brain-like Intelligence Technology of China","National Key Research and Development Program of China","the National Natural Science Foundation of China"],"pagination":["1322"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11980293"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["Background
Hypertension can lead to an increased risk of heart failure and death. The life's essential 8 (LE8) is an eight-factor measure of cardiovascular health recently released by the American Heart Association for use in measuring cardiovascular health. However, evidence on the beneficial effects and necessity of LE8 control is still lacking, especially for hypertension.Methods
The study population was drawn from the Kailuan cohort, hypertensive population at baseline with the non-hypertensive population matched 1:1 according to age and sex were involved in this analysis. The cut off value for each factor in LE8 was 50 (≥ 50 as controlled, < 50 as uncontrolled). The primary outcomes involved heart failure and all-cause mortality. Cox proportional risk regression models"],"journal":["BMC public health"],"pubmed_title":["The role of the control of \"life's essential 8\" for prevention on heart failure and all-cause mortality in patients with hypertension: the Kailuan cohort study."],"pmcid":["PMC11980293"],"funding_grant_id":["82288101","82171514","2021ZD0200800","M23013","2019YFA0706200","2021ZD0202100"],"pubmed_authors":["Wu J","Meng S","Bao Y","Wu S","Qin X","Wang F","Chen X","Shi J","Wang J","Li L"],"additional_accession":[]},"is_claimable":false,"name":"The role of the control of \"life's essential 8\" for prevention on heart failure and all-cause mortality in patients with hypertension: the Kailuan cohort study.","description":"Background
Hypertension can lead to an increased risk of heart failure and death. The life's essential 8 (LE8) is an eight-factor measure of cardiovascular health recently released by the American Heart Association for use in measuring cardiovascular health. However, evidence on the beneficial effects and necessity of LE8 control is still lacking, especially for hypertension.Methods
The study population was drawn from the Kailuan cohort, hypertensive population at baseline with the non-hypertensive population matched 1:1 according to age and sex were involved in this analysis. The cut off value for each factor in LE8 was 50 (≥ 50 as controlled, < 50 as uncontrolled). The primary outcomes involved heart failure and all-cause mortality. Cox proportional risk regression models","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-07-13T03:04:31.428Z","creation":"2025-07-13T03:04:31.428Z"},"accession":"S-EPMC11980293","cross_references":{"pubmed":["40200231"],"doi":["10.1186/s12889-025-22422-y"]}}