biostudies-literatureUnknown10(4)Harris G<h4>Purpose</h4>To prospectively document the outcomes of patients treated with palliative radiation therapy (RT) who are receiving immunotherapy.<h4>Methods and materials</h4>Patients with advanced cancer receiving or planning to commence immunotherapy within 28 days who were referred for palliative RT at our center between January 2017 and September 2019 were screened for participation in this prospective observational study. Demographic and treatment data, along with patient-reported outcomes (PROs) using the Edmonton Symptom Assessment Scale for cancer, were collected at baseline, after 1 month, and then every 3 months for up to 1 year or until death. RT dose and fractionation were at the discretion of the treating radiation oncologist. Immunotherapy was given as per the standard of caAdvances in radiation oncology101741https://www.ebi.ac.uk/biostudies/studies/S-EPMC11982977biostudies-literatureProspective Study of Patients Treated with Palliative Radiation Therapy While on Immunotherapy.PMC11982977Wong RKSLiu ZABang ARingash JCummings BMillar BAHarris GBezjak ADawson LAfalseProspective Study of Patients Treated with Palliative Radiation Therapy While on Immunotherapy.<h4>Purpose</h4>To prospectively document the outcomes of patients treated with palliative radiation therapy (RT) who are receiving immunotherapy.<h4>Methods and materials</h4>Patients with advanced cancer receiving or planning to commence immunotherapy within 28 days who were referred for palliative RT at our center between January 2017 and September 2019 were screened for participation in this prospective observational study. Demographic and treatment data, along with patient-reported outcomes (PROs) using the Edmonton Symptom Assessment Scale for cancer, were collected at baseline, after 1 month, and then every 3 months for up to 1 year or until death. RT dose and fractionation were at the discretion of the treating radiation oncologist. Immunotherapy was given as per the standard of ca2025-01-01T00:00:00Z2025 Apr2025-07-07T03:09:11.74Z2025-07-07T03:09:11.74ZS-EPMC119829774021331110.1016/j.adro.2025.101741