biostudies-literatureUnknown25(1)Sen E<h4>Purpose</h4>The environmental impact and cost of volatile anesthetics are significant concerns in modern anesthesia. Automated end-tidal control systems aim to optimize anesthetic delivery by reducing waste and improving efficiency. This study compared the effectiveness of end-tidal controlled (EtControl) low-flow anesthesia to manually controlled (MC) low-flow anesthesia in elective surgeries.<h4>Design</h4>A randomized controlled trial.<h4>Methods</h4>This study was conducted with 132 ASA Class I-II patients undergoing elective surgeries under general anesthesia. Patients were randomly assigned to the EtControl (n = 66) or MC (n = 66) groups. The primary outcomes included anesthetic agent consumption (mL).<h4>Findings</h4>Anesthetic consumption was similar between the EtControl groupBMC anesthesiology176https://www.ebi.ac.uk/biostudies/studies/S-EPMC11987261biostudies-literatureThe effects of end-tidal controlled low-flow anesthesia on anesthetic agent consumption in elective surgeries: randomized controlled trial.PMC11987261Sen EMizrak AUgur BKGanidaglı SYildiz FCesur MPirbudak LfalseThe effects of end-tidal controlled low-flow anesthesia on anesthetic agent consumption in elective surgeries: randomized controlled trial.<h4>Purpose</h4>The environmental impact and cost of volatile anesthetics are significant concerns in modern anesthesia. Automated end-tidal control systems aim to optimize anesthetic delivery by reducing waste and improving efficiency. This study compared the effectiveness of end-tidal controlled (EtControl) low-flow anesthesia to manually controlled (MC) low-flow anesthesia in elective surgeries.<h4>Design</h4>A randomized controlled trial.<h4>Methods</h4>This study was conducted with 132 ASA Class I-II patients undergoing elective surgeries under general anesthesia. Patients were randomly assigned to the EtControl (n = 66) or MC (n = 66) groups. The primary outcomes included anesthetic agent consumption (mL).<h4>Findings</h4>Anesthetic consumption was similar between the EtControl group2025-01-01T00:00:00Z2025 Apr2026-06-02T04:18:57.705Z2026-04-14T03:14:02.339ZS-EPMC119872614021713310.1186/s12871-025-03051-9