{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["61(5)"],"submitter":["Castelein J"],"pubmed_abstract":["<h4>Background</h4>Cardiac magnetic resonance elastography (MRE) shows promise in assessing the mechanofunctional properties of the heart but faces clinical challenges, mainly synchronization with cardiac cycle, breathing, and external harmonic stimulation.<h4>Purpose</h4>To determine the reproducibility of in vivo cardiac multifrequency MRE (MMRE) for assessing diastolic left ventricular (LV) stiffness and viscosity.<h4>Study type</h4>Prospective.<h4>Subjects</h4>This single-center study included a total of 28 participants (mean age, 56.6 ± 23.0 years; 16 male) consisting of randomly selected healthy participants (mean age, 44.6 ± 20.1 years; 9 male) and patients with aortic stenosis (mean age, 78.3 ± 3.8 years; 7 male).<h4>Field strength/sequence</h4>3 T, 3D multifrequency MRE with a sin"],"journal":["Journal of magnetic resonance imaging : JMRI"],"pagination":["2146-2154"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11987795"],"repository":["biostudies-literature"],"pubmed_title":["Reproducibility of Cardiac Multifrequency MR Elastography in Assessing Left Ventricular Stiffness and Viscosity."],"pmcid":["PMC11987795"],"pubmed_authors":["Hansen AE","Kettless K","Anders MS","De Backer O","Duus AS","Castelein J","Sack I","Dierckx RAJO","Vejlstrup NG","Borra RJH","Lund MAV","Bække PS"],"additional_accession":[]},"is_claimable":false,"name":"Reproducibility of Cardiac Multifrequency MR Elastography in Assessing Left Ventricular Stiffness and Viscosity.","description":"<h4>Background</h4>Cardiac magnetic resonance elastography (MRE) shows promise in assessing the mechanofunctional properties of the heart but faces clinical challenges, mainly synchronization with cardiac cycle, breathing, and external harmonic stimulation.<h4>Purpose</h4>To determine the reproducibility of in vivo cardiac multifrequency MRE (MMRE) for assessing diastolic left ventricular (LV) stiffness and viscosity.<h4>Study type</h4>Prospective.<h4>Subjects</h4>This single-center study included a total of 28 participants (mean age, 56.6 ± 23.0 years; 16 male) consisting of randomly selected healthy participants (mean age, 44.6 ± 20.1 years; 9 male) and patients with aortic stenosis (mean age, 78.3 ± 3.8 years; 7 male).<h4>Field strength/sequence</h4>3 T, 3D multifrequency MRE with a sin","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 May","modification":"2025-07-13T03:06:08.895Z","creation":"2025-07-13T03:06:08.895Z"},"accession":"S-EPMC11987795","cross_references":{"pubmed":["39449547"],"doi":["10.1002/jmri.29640"]}}